Preimplantation
Genetic Testing for Aneuploidy

At Ingenes, we offer preimplantation genetic testing for aneuploidy (PGT-A), an embryonic selection technique designed to increase the probability of reproductive success by selecting chromosomally normal embryos.

PGT-A genetic testing helps ensure that only embryos with the correct number of chromosomes are transferred during IVF, which reduces the risk of miscarriage and genetic disorders. Our center uses the latest technology to carefully analyze each embryo, allowing us to offer the highest level of care.

How Does PGT-A work?

PGT-A testing works by screening embryos created through in vitro fertilization (IVF) for chromosomal abnormalities before implantation.

During the IVF process, eggs are retrieved and fertilized with sperm in the lab. After the embryos have developed for a few days, a small sample of cells is taken from each embryo.

This sample is then analyzed using advanced genetic techniques. The PGT preimplantation genetic testing helps identify embryos with the correct number of chromosomes, also known as euploid embryos. These embryos are more likely to result in a successful pregnancy. The embryos that are found to be chromosomally normal can then be selected for transfer.

Are there different types of PGT?

Yes, there are different types of PGT (Preimplantation Genetic Testing) designed for various purposes.

Preimplantation genetic testing for aneuploidy PGT-A screens embryos for chromosomal abnormalities, ensuring they have the correct number of chromosomes.
Another type of preimplantation testing is PGT-M. This test detects monogenic disorders which are specific inherited genetic diseases like cystic fibrosis or Tay-Sachs disease.
PGT-SR is used to identify structural rearrangements in chromosomes, such as translocations or inversions.

Each type of PGT offers targeted genetic testing to address different reproductive challenges. By selecting the right form of PGT, couples can improve their chances of having a healthy baby, free from chromosomal or genetic conditions, through IVF treatment.

The most important causes preventing parents from becoming pregnant are due to the genetics of the embryo. By analyzing the chromosomes of your embryos, the chances of giving birth to a healthy baby increase.

Could you be eligible for a PGT-A test?

PGT-A is mainly recommended for individuals who fall under the following groups:

•Women who are 37 years old or older due to the increased risk of chromosomal abnormalities as they age.

•Men who are 38 years old or older due to the increased risk of chromosomal abnormalities as they age.

•Women with a history of pregnancy loss or recurrent miscarriages.
Women with a history of implantation failure.

•Women who have experienced a decline in the quality of their eggs due to conditions such as endometriosis, polycystic ovary syndrome, or low egg production.

In addition, those who wish to choose the sex of their baby can also opt to undergo this test. By analyzing the sex chromosomes, PGT-A allows for preimplantation sex determination by selecting and transferring the embryos of the desired sex.

PGT-A can also be recommended for couples who have experienced multiple failed IVF cycles without a known cause. Testing the embryos before implantation helps identify chromosomal abnormalities that might have gone unnoticed in the past.

For those with a family history of chromosomal abnormalities, PGT-A provides an extra layer of security by helping avoid potential genetic disorders. This test offers peace of mind to families who want to increase their chances of a successful pregnancy and reduce the risk of genetic issues.

How is the Preimplantation Genetic Test for Aneuploidy carried out?

At Ingenes, preimplantation genetic testing for aneuploidy (PGT-A) is performed with precision and care to increase the chances of a healthy pregnancy.

1

This procedure is carried out at an In Vitro Fertilization (IVF) Laboratory by an Assisted Reproduction specialized biologist, who will carefully select the embryos with the best potential for analysis. Genomic analysis is used to identify which embryos have the correct number of chromosomes, ensuring that only chromosomally normal embryos are selected for transfer.

2

This technique begins with the biopsy collection without interfering with embryo development on the 3rd, 5th, or 6th day of development, to be analyzed with the help of advanced molecular biology techniques, using the best available technology on the market, Next Generation Sequencing (NGS).

3

Genomic analysis is used to identify chromosomally normal embryos and determine their sex for selection and transfer during assisted reproduction treatments.

PGT-A genetic testing also allows for the identification of the embryos’ sex, offering an extra option for parents who want to select the sex of their baby. PGT-A genetic testing is especially useful for couples at higher risk for chromosomal abnormalities, such as older parents or those with a history of recurrent miscarriages. The accuracy and thoroughness of preimplantation genetic testing PGT help to improve success rates in assisted reproduction treatments. If you have any questions about PGT-A or are considering using this test to gain assurance about your future baby’s well-being, your Assisted Reproduction expert will assess your case and guide you through this process.

What syndromes can be prevented with PGT-A?

PGT-A helps prevent the development of syndromes, a few of the most common ones include:

• Down syndrome (+21)
• Patau syndrome (+13)
• Edwards syndrome (+18)
• Klinefelter syndrome (XXY)
• Turner syndrome (OX)
• Triple X syndrome (XXX)
• Jacobs syndrome (XYY)
• Among other anomalies.

When undergoing assisted reproduction, your specialist will identify embryos with abnormalities and only select those that have the best chromosomal composition and do not show any genetic irregularities in terms of numbers. Transferring these selected embryos will increase the chances of a successful pregnancy.

PGT-A Test reduces risk of miscarriage.

Leave your baby's health in expert hands

Our research team is dedicated to innovation and education in reproductive sciences. These steps include developing cutting-edge technology and tests such as preimplantation genetic testing for aneuploidy (PGT-A).

In partnership with world-renowned researchers from Cinvestav-IPN, we ensure that you have access to the latest advancements in reproductive medicine. By integrating innovation and education, our institute stays at the forefront of assisted reproduction.

Our team of skilled specialists works tirelessly to provide you with the most accurate and reliable results. Rest assured, when you choose Ingenes, your future baby's health is in the hands of experts committed to delivering the best care.

Reach out to us and find the assurance you need with PGT-A

By donating sperm, healthy men help others achieve their dreams of having a family. Sperm donation centers are a safe, confidential way to take part in this life-changing act. These centers carefully select donors to ensure the highest quality sperm is available for those in need. Sperm donation is a generous act that makes a significant difference in the lives of many families.

Are you ready to take the steps necessary to create your future family? Get in touch with us today. Let us help you rule out genetic abnormalities in chromosomal numbers. Click on the following button to schedule your appointment and have our experts determine if you are a candidate for this test.

If you’re ready to find the assurance you need with PGT-A genetic testing, reach out to us today. Implantation tests, preimplantation genetic testing, PGT options, plus more will rule out chromosomal abnormalities. You can look forward to having a peace of mind about your journey to parenthood and enjoy the process.

Our experts are here to guide you through the process and determine if you are a candidate for this test or others. Genetic testing doesn’t have to be overwhelming anymore.

Preimplantation Genetic Testing for Aneuploidy