Denisse had undergone 3 artificial inseminations and 2 IVF cycles without success and was about to give up on becoming a mother. Today she shares how, after a precise diagnosis of uterine fibroids and a personalized multicycle treatment, she was able to hold her first daughter.
How does uterine fibroids affect your long-term fertility?
Uterine fibroids (leiomyomas or fibroids) are benign growths in the uterine muscle. In Denisse’s case, a fibroid in the cervix hindered embryo implantation. If left untreated, fibroids larger than 2 cm can distort the uterine cavity, reduce endometrial blood flow, and increase miscarriage risk.
Avoid self-medication. It’s best to consult a Reproductive Medicine specialist before any treatment if your goal is pregnancy.
Why do some treatments fail without a correct diagnosis?
Without accurate imaging (ultrasound, MRI) or specialized evaluation, treatments can be repeated without success. In Denisse’s case, the fibroid went unnoticed in her first 5 procedures, leading to frustration, wasted time, and more stress.
Before trying any medication, see a Reproductive Medicine specialist to optimize your chances.
Advantages of a personalized multicycle treatment
At Ingenes we design a multicycle program integrating endocrinology, embryology, and reproductive biology. We adjust FSH dosage (150–300 IU), stimulation timing, and transfer date for an optimal endometrium (7–10 mm) and high-quality embryos.
In Denisse’s case, we removed the fibroid and scheduled a tailored cycle. After transfer, she got a positive β-hCG and experienced the joy of hearing the heartbeat on the ultrasound.
What’s included in the Initial Program at Ingenes?
With our “Facing Infertility” Initial Program you will receive:
- Complete evaluation: ultrasound, hormone panel (FSH, LH, AMH), and semen analysis.
- Personalized protocol with embryologists, gynecologists, and psychotherapists.
- Continuous monitoring to adjust doses and maximize implantation (> 50% per cycle).
If you’ve tried everything, don’t give up—Thousands of patients have found their path to parenthood with us.
Take the next step
Schedule your Initial Program and let us support you so that soon you can bring your baby home.
Frequently Asked Questions
1. What initial tests are needed?
We recommend assessing ovarian reserve (AMH, FSH, LH), tubal patency (hysterosalpingography or sonohysterography), and a semen analysis. A transvaginal ultrasound detects fibroids, polyps, and measures the endometrium. Early diagnosis saves failed cycles and stress.
2. How do fibroids affect IVF?
Fibroids can distort the uterine cavity and alter vascularization, reducing IVF success rates by up to 30% when over 3 cm. Prior myomectomy often significantly improves pregnancy chances.
3. Is controlled ovarian stimulation safe?
Under medical supervision, adjusting FSH (150–300 IU/day) and frequent ultrasound monitoring minimizes ovarian hyperstimulation syndrome (< 2%). We evaluate age, BMI, and hormones for a safe and effective protocol.
4. Can I try insemination after an IVF failure?
If your ovarian response is good and sperm quality adequate, intrauterine insemination may be considered. But with tubal blockage or very low ovarian reserve, IVF is usually the best option.
References
- American Society for Reproductive Medicine. (2020). Uterine Fibroids and Reproductive Outcomes. Fertility and Sterility. https://doi.org/10.1016/j.fertnstert.2020.05.023
- MedlinePlus. (2023). In Vitro Fertilization. https://medlineplus.gov/ency/article/007277.htm
- ASRM Practice Committee. (2017). Diagnostic evaluation of the infertile female. Fertility and Sterility, 108(3), 409–418. https://doi.org/10.1016/j.fertnstert.2017.05.042
- NICHD. (2019). Assisted Reproductive Technology (ART). https://www.nichd.nih.gov/health/topics/infertility/conditioninfo/causes
We’re with you every step of the way. If you have questions or want a personalized evaluation, consult a reproductive specialist and take the first step toward your dream of becoming a parent.