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Many people may be familiar with the efforts of promoting breast cancer awareness during its commemorative month, however, a lesser-explored aspect of the disease is its effect on reproductive health and vice-versa, our reproductive history may give us hints of risk factors that influence the propensity to develop this type of cancer, let’s keep in mind that even though women are statistically most propense, this disease affects both women and men. Risk factors There are several propensity factors for developing breast cancer, both controllable and uncontrollable: Prolactin’s role Prolactin is a hormone produced by both men and women, it is associated with the development breast growth and lactation, however new studies have suggested that there is a relationship between prolactin production and the development of breast cancer. At Ingenes, part of the evaluations of the reproductive health of our patients includes a measurement of prolactin levels, that serves as an important fertility indicator. Keeping in mind that this hormone alone cannot provide a final diagnosis, but it provides relevant information to understand the state of the ovarian reserves. Chemotherapy’s side effects on fertility It is important to know that chemotherapy is a common cause of infertility, so it is not uncommon to encounter cancer patients and survivors who wish to learn more about the various treatment and fertility options available. Breast self-examination and annual check-ups Performing routine self-examinations is a recommendable habit, according to the self-examination manuals created by the Mexican Institute of Social Security, these should be carried out 7 days after menstruation, it is important to create a routine and become acquainted with our bodies in order to identify any abnormalities in a timely manner, in addition to this, it is advisable to start an annual breast cancer screening by mastography at 40 years of age, however, if there is a family history of breast cancer, it is advisable to begin screening at 30 years of age.

World Health Day invites us to consider all the factors that influence having a child. From our physical health and lifestyle to environment and socioeconomic conditions, every detail counts. Understanding how these aspects combine can make a difference when building a family. How does physical health affect fertility? Physical health of both partners is essential to conceive and carry a pregnancy to term. Conditions like obesity (BMI >30 kg/m²), type 2 diabetes, thyroid disorders or STIs can damage eggs and sperm. After age 35, ovarian reserve declines and sperm quality decreases by 1–2 % each year. Avoid self-medication and always seek professional guidance. Before taking supplements or medications, consult an assisted reproduction specialist. Early and personalized diagnosis increases your chances of success. How does lifestyle affect your chances of conceiving? Smoking, consuming more than 14 units of alcohol per week or using illicit drugs can damage the DNA of eggs and sperm. A diet rich in folates, omega-3 and vitamins D and E promotes a healthy uterine environment and sperm quality. Doing at least 150 minutes of moderate exercise weekly helps balance hormones. Relaxation techniques like yoga or mindfulness also reduce stress and support ovulation and spermatogenesis. What impact does environment have on your reproductive capacity? Pollution and exposure to toxins (phthalates, pesticides) can lower sperm count and disrupt ovarian function. Chronic stress raises cortisol, hindering reproductive hormone production. Improve your surroundings: ensure good ventilation, get enough sleep and minimize household pollutants to protect your fertility. Why do socioeconomic factors matter in the decision to become a parent? Having economic stability and access to quality healthcare influences when you decide to have children and how many. Job or social insecurity often delays parenthood or limits family size. Education and reliable information allow you to plan freely and confidently. Rely on official sources to make informed decisions. How does mental health affect your fertility? Anxiety and depression reduce libido and can disrupt the menstrual cycle. Facing fertility challenges without emotional support increases psychological strain. Seeking psychological support at fertility centers strengthens your resilience and improves treatment adherence. What advances does assisted reproduction offer today? Techniques such as in vitro fertilization (IVF) and artificial insemination have helped many couples. However, their cost (between 8,000 and 15,000 USD per cycle) and emotional impact require robust support. Learn more in World Sexual Health Day: A Holistic View of Wellness and Fertility and World Fertility Day: A Date to Inform, Empathize, and Never Lose Hope. On this World Health Day, let’s commit to habits and environments that nurture our reproductive health. With information, empathy and comprehensive care, we can support you at every step toward parenthood. Frequently Asked Questions (FAQ) 1. What Is the Best Age to Conceive? The ideal range is usually between 20 and 30 years, when ovarian reserve and egg quality are optimal. After 35, fertility declines and the risk of genetic abnormalities increases. Every body is unique. An assisted reproduction specialist will help you evaluate hormones like AMH and FSH to plan more safely. 2. How Does Body Weight Affect Fertility? A BMI below 18.5 or above 30 can disrupt menstrual cycles and sperm quality. Fat tissue produces estrogens that unbalance hormones. A personalized nutrition plan under medical supervision helps reach a healthy BMI and increases your chances of conceiving. 3. What Diagnostic Tests Are Recommended Before Trying to Get Pregnant? Ideally, a hormonal profile (FSH, LH, AMH, TSH), a semen analysis and tubal patency studies (hysterosalpingography). These tests identify potential obstacles early. It’s also advisable to assess ovarian reserve and conduct a general health check—thyroid profile, glucose and liver function—to design a successful reproductive plan. 4. Is Psychological Support Necessary During Assisted Fertility? Yes. Stress and anxiety can lower implantation rates and affect your well-being. Psychological help improves treatment adherence and provides emotional tools at each stage. Support groups, individual or couple therapy and relaxation techniques are valuable complements to strengthen your reproductive journey. Sources American Society for Reproductive Medicine. (2020). Practice Committee guidelines. Reproductive Medicine. doi:10.1016/j.fertnstert.2020.03.028 MedlinePlus. (2023). Infertility: Overview. https://medlineplus.gov/infertility.html World Health Organization. (2021). Reproductive health indicators. https://www.who.int/reproductive-health/ Practice Committee of the American Society for Reproductive Medicine. (2015). Testing and interpreting semen analysis in infertility evaluation. Fertility and Sterility, 103(3), e18–e25. doi:10.1016/j.fertnstert.2015.01.016 Remember that every story is unique. For personalized support and answers to your questions, consult an assisted reproduction specialist. You are not alone on this journey!

The journey to parenthood is unique for each couple, and an accurate diagnosis is the essential first step. At Ingenes, we understand that every detail counts on the path to having a baby at home. The Importance of an Accurate Medical Diagnosis An accurate medical diagnosis is essential to chart a clear path in fertility treatment. Correctly identifying the causes of infertility not only makes it easier to select the most appropriate treatment but also gives couples a deeper understanding of their situation. This is crucial to managing emotions and expectations during this process. The Five Pillars of Fertility The Importance of a Timely Diagnosis A timely and accurate diagnosis can be the difference between years of unsuccessful treatments and a successful path to motherhood. At Ingenes, 90% of our patients arrive after having gone through exhausting experiences, both physically and emotionally. Therefore, our focus is on avoiding the loss of valuable time and providing fast and accurate diagnoses. Technology and Expertise at Ingenes We have cutting-edge technology and a team of highly trained specialists in various areas of assisted reproduction. This allows us to offer a clear diagnosis and a personalized treatment plan from the first consultation. Understanding and Managing Infertility Understanding the causes of infertility and the details of treatment helps couples better manage the situation. At Ingenes, we strive to provide not only medical advice but also emotional support, so that each couple feels safe and understood at every stage of the process. At Ingenes, your dream of having your baby at home is our priority. We understand that the path to fertility can be complicated, but with an accurate diagnosis and proper treatment, we are here to help you turn that dream into reality. If you are looking to have a baby at home and want to better understand your fertility situation, visit Ingenes. Our experts are ready to guide you every step of your journey. Contact us today to start your path to parenthood.

Diabetes mellitus is characterized by high blood glucose levels and, if left uncontrolled, can affect a man’s fertility in several ways. The first step in controlling diabetes is to eat a healthy diet and exercise regularly. If this is not enough, you may need to take medication or insulin injections. Diabetes treatment is usually enough to restore fertility. Otherwise, in vitro fertilization with intracytoplasmic sperm injection (IVF+ICSI) is the treatment of choice to achieve pregnancy. It is advisable to perform a sperm DNA fragmentation test before starting any assisted reproduction treatment since diabetes mellitus damages sperm DNA and a high fragmentation rate could affect the success rates of these procedures. What is diabetes mellitus? Diabetes mellitus is a disease in which the body does not produce enough insulin or does not use it properly. Insulin is a hormone that transforms sugar, starch, and other foods into the energy we need daily. According to data from the World Health Organization, diabetes mellitus affects 200 million people worldwide, and it is estimated that by 2030 there will be 366 million diabetics. Diabetes mellitus is characterized by high levels of glucose in the blood and if not controlled can affect a man’s fertility in several ways: Women with uncontrolled diabetes may have ovulation problems or be more prone to cervical-vaginal infections. Similarly, high blood sugar levels increase the risk of miscarriage and can cause birth defects in the fetus or even lead to excessive growth (macrosomia) and complications during delivery. The main symptoms of diabetes mellitus The main symptoms of diabetes mellitus are: If you have any of these symptoms you should consult a doctor immediately, as timely treatment of diabetes can prevent various health problems. Causes of diabetes mellitus Diabetes mellitus occurs because the body does not produce enough insulin or does not use it properly. Some factors that increase the likelihood of developing diabetes include: It is important to note that diabetes can be hereditary and men with parents or brothers who suffer from it are more likely to develop it. How is diabetes mellitus diagnosed? In addition to a physical examination and a review of the patient’s medical history, a fasting blood glucose test is necessary. A person with a blood glucose level of 126 mg/dl or higher has diabetes and should be treated. People with diabetes mellitus need to have regular tests to make sure their glucose levels are under control. If you have had trouble conceiving and are overweight or if someone in your family has diabetes, it is recommended that you have a blood test to rule out this disease. Treatments for achieving pregnancy when you have diabetes mellitus The first step to controlling diabetes is to eat a healthy diet and exercise regularly. If this is not enough to keep your blood sugar levels under control, you may need to take medications such as sulfonylureas and metformin or take insulin injections. Diabetes treatment is usually enough to restore fertility. Diabetics under good medical control, with good body weight and normal blood glucose and cholesterol levels, usually have better quality semen and ejaculate normally. Otherwise, in vitro fertilization with intracytoplasmic sperm injection (IVF+ICSI) is the treatment of choice to achieve pregnancy because it makes it possible to inject a single sperm directly into the cytoplasm of a mature egg using a microscopic needle. It is advisable to perform a sperm DNA fragmentation test before starting any assisted reproduction treatment since a high fragmentation rate could affect the success rates of these procedures. In the case of a man suffering from anejaculation or if there are no good quality sperm in the ejaculate, it is possible to recover them using epididymal aspiration or testicular biopsy. Patients with erectile dysfunction can take medication to restore erections. It is important to note that in cases of retrograde ejaculation, it is possible to recover sperm directly from urine to use in assisted reproduction treatments after a washing process.

Every August 31 we celebrate International Day of Obstetrics and Pregnant Women, a tribute to those who accompany every heartbeat and every step on the journey to new life, with empathy, science, and dedication.At Ingenes, this day is an opportunity to recognize our Gynecology, Obstetrics, and Reproductive Medicine team. We support women and pregnant people who dream of becoming mothers, often after years of attempts, failed treatments, or complex diagnoses. Today we honor every story, every birth, and every small yet significant achievement. What is obstetrics and what is it for? Obstetrics is the branch of medicine that oversees pregnancy, childbirth, and the postpartum period, caring for the health of both mother and baby. Its work goes beyond delivery: it begins before conception. In assisted reproduction, it integrates with gynecology, reproductive biology, and genetics to offer personalized care. This way we detect and prevent complications, creating an environment of trust and safety during such an important stage. What is the origin of International Day of Obstetrics? It is celebrated on August 31 in honor of Saint Raymond Nonnatus, patron of pregnant women and childbirth, born by Caesarean section after his mother’s death. Today the date highlights obstetricians, midwives, and health professionals dedicated to care before and after birth. It also aims to promote ethical, modern, respectful, and accessible care for everyone who wishes to have a child. How does obstetrics relate to assisted reproduction? In fertility treatments, obstetrics takes on profound meaning. Many patients come to Ingenes after years of unsuccessful attempts or after hearing “there are no more options.” Our support begins with hope. We assess each person’s hormonal, uterine, ovarian, and emotional state, guiding them from investigating causes of infertility to monitoring the first weeks of pregnancy. Thanks to technologies like IVF, the exclusive IVF MORE® technique, and genetic and hormonal tests, we personalize every step with science and empathy. Why does Ingenes stand out in obstetrics at the beginning of thousands of stories? With over 20 years of experience, Ingenes has helped more than 75,000 families bring a baby home. Behind each story is a team of professionals who combine expertise and humanity. Our doctors, certified in Gynecology and Obstetrics with subspecialties in Reproductive Medicine, Clinical Embryology, and Genetics, conduct from the first consultation a comprehensive evaluation—physical, reproductive, emotional, and social—to design tailored treatments. Once pregnancy is achieved, obstetric follow-up continues, prioritizing health, well-being, and emotional bonding. How does early obstetric care benefit your fertility? Obstetrics not only supports pregnancy: early monitoring improves your chances of conceiving. If you are over 35, have been trying for several months without success, or suffer from endometriosis, PCOS, blocked fallopian tubes, or a history of pregnancy loss, it’s key to seek specialized help as soon as possible. At any of our 19 locations in Mexico and the U.S., you can schedule your first consultation for a complete evaluation and personalized treatment plan. Avoid self-medicating without medical guidance; consult a specialist in Assisted Reproduction to increase your chances of pregnancy. How to celebrate this day and your desire to become a mother? International Day of Obstetrics is a time to give thanks and look to the future with hope. Recognizing those who protect life is also honoring your desire to build a family. If your baby hasn’t arrived yet, if you feel you’ve tried everything, or are just starting this journey, this day is yours. Honoring obstetrics is honoring your dream. Learn more about compassionate care in reproductive medicine on National Nurses Day: The Human Heart of Reproductive Medicine and discover the impact of science on Celebrating Hope and Science on World Fertility Day. Frequently Asked Questions What does obstetric follow-up in assisted reproduction involve? It includes periodic visits with ultrasounds (crown-rump length measurement in mm), hCG and progesterone tests, blood pressure monitoring (mmHg), and weight checks (kg). We also offer emotional support and nutritional counseling (balanced diet, moderate exercise) to optimize pregnancy and reduce risks such as preeclampsia or intrauterine growth restriction. When should I consult an obstetrician if I plan to conceive? A preconception visit is recommended if you are over 35, have had spontaneous abortions, chronic conditions (diabetes, hypertension), or previous fertility treatments. We assess immunology (immunoglobulins, Rh), hormones (FSH, LH, AMH in pg/mL), and anatomy (uterine and fallopian tube ultrasound) to design a strategy that increases your chances of conceiving, including supplements like folic acid (400 µg daily). How does IVF MORE® technology help in the obstetric process? IVF MORE® optimizes embryo selection through morphological and genetic evaluation (PGT-A), reducing miscarriage and increasing implantation. It synchronizes endometrial thickness (mm) with embryo development, and early obstetric monitoring tracks the heartbeat from week 6 and adjusts hormonal supplements (progesterone 600 mg/day) for an optimal first trimester. What role do midwives play in modern obstetric care? Midwives provide a holistic approach, supporting respectful birthing techniques and emotional care. They collaborate with obstetricians in detecting warning signs, prenatal education, vital sign monitoring, and breastfeeding guidance. Their involvement reduces unnecessary interventions (C-sections, episiotomies) and empowers you to participate in decisions about your birth. Sources MedlinePlus. Obstetric care. Retrieved from https://medlineplus.gov/obstetriccare American College of Obstetricians and Gynecologists. (2022). Obstetric care consensus. DOI:10.1097/AOG.0000000000000000 World Health Organization. (2018). WHO recommendations: Intrapartum care for a positive childbirth experience. Retrieved from https://www.who.int/publications/i/item/9789241550215 National Institute for Health and Care Excellence. (2020). Fertility problems: assessment and treatment. Retrieved from https://www.nice.org.uk/guidance/cg156 On this International Day of Obstetrics, remember you are not alone: every step counts and every story matters. Consult a specialist in assisted fertilization to receive the care you deserve and give the best welcome to the new life you hope for.

Uterine myomatosis is the formation of myomas or fibroids inside the uterus. These are benign tumors classified according to their location. Depending on where they are found, fibroids are classified as: Intramural: within the muscular wall of the uterus. They can affect fertility if they exceed 4 cm. Submucosal: on the surface of the uterine lining. They hinder embryo implantation. Subserosal: in the outer layer of the uterus. They usually do not interfere with fertility. What is uterine myomatosis and why does it matter for fertility? Uterine myomatosis involves the growth of fibroids, benign smooth muscle tumors, inside the uterus. It affects about 20% of women of reproductive age, especially after age 30. Fibroids can range from microscopic nodules to masses over 4 kg, altering the shape of the uterus and reducing pregnancy chances. How common is uterine myomatosis in those trying to conceive? Uterine fibroids are the most common pelvic tumors in women of reproductive age, present in nearly 70–80% before menopause. Although many are asymptomatic, those that deform the uterine cavity—particularly large intramural and submucosal fibroids—are involved in up to 80% of uterine factor infertility cases. How do fibroids affect embryo implantation? Large submucosal and intramural fibroids can: Alter sperm transport and uterine peristalsis Reduce endometrial receptivity by compressing the lining Increase the risk of implantation failure and early miscarriage Can fibroids complicate pregnancy? Yes. During pregnancy, fibroids can cause: Higher risk of miscarriage and preterm birth Fetal growth restriction due to lack of space Cervical canal obstruction or labor dystocia Postpartum hemorrhage from poor uterine contraction What symptoms may indicate fibroids? About 25% are asymptomatic. When symptoms occur, they include: Sensation of pelvic pressure or heaviness Heavy or prolonged menstrual bleeding Pelvic cramps and irregular bleeding Frequent urination or difficulty urinating Secondary infertility or recurrent miscarriages Severity depends on fibroid size, number, and location. How is diagnosis confirmed? Transvaginal ultrasound is the gold standard, with nearly 100% sensitivity (95% transabdominal). In complex cases, MRI is used. Always consult a reproductive medicine specialist to interpret results and design a treatment plan. Fertility-preserving treatment options Choice depends on age, fibroid characteristics, and reproductive goals: Expectant management for small, asymptomatic fibroids Myomectomy (surgical removal), followed by assisted reproduction techniques Controlled ovarian stimulation combined with in vitro fertilization (IVF) if cavity distortion persists IVF bypasses uterine transport obstacles and allows for selecting the embryo with the highest implantation potential. For more information, see our guide on Endometriosis: what it is and how it impacts fertility. FAQ 1. Can small fibroids disappear on their own? Yes. Many remain stable or shrink after menopause due to estrogen decline. In reproductive age, asymptomatic fibroids under 2 cm are usually monitored with periodic ultrasounds. If you plan to conceive, even a small submucosal fibroid can affect implantation, so consult your doctor to assess intervention before trying to conceive. 2. Are there non-surgical treatments? GnRH agonists and selective progesterone receptor modulators can temporarily shrink fibroids and reduce bleeding in 3–6 month cycles. They improve conditions before surgery or comfort but are not definitive solutions. Never self-medicate without medical supervision. 3. When can I attempt IVF after a myomectomy? Ideally between 6 and 12 months after surgery, before recurrence risk increases. This timing allows the uterine lining to heal and optimizes pregnancy chances. Make sure your specialist confirms proper healing with ultrasound or hysteroscopy before starting treatment. 4. Does the risk of miscarriage increase? Yes. Fibroids that deform the cavity or alter blood flow are associated with early pregnancy loss. Risk increases with fibroid size and location, especially submucosal and large intramural fibroids. Proper management, surgical or with assisted reproduction, significantly reduces miscarriage rates. Always consult a specialist before making decisions. References Faerstein, E., Szklo, M., & Schwingl, P. J. (2001). Risk factors for uterine leiomyoma: a practice-based case–control study. American Journal of Epidemiology, 153(5), 463–469. doi:10.1093/aje/153.5.463 Lau, W., & Shlisselberg, S. (2016). Management of uterine fibroids. American Family Physician, 94(2), 106–113. https://www.aafp.org/afp/2016/0715/p106.html MedlinePlus. (2021). Uterine fibroids. https://medlineplus.gov/uterinefibroids.html Stewart, E. A. (2015). Uterine fibroids. Lancet, 376(9745), 145–157. doi:10.1016/S0140-6736(10)60246-1 Remember: every body is unique. Stay informed, keep hope, and consult an assisted reproduction specialist for personalized care.

Low ovarian reserve is a condition that impacts a woman’s fertility, characterized by a reduced number and lower quality of eggs in the ovaries. Although it usually appears after age 35, genetic, environmental factors and certain diseases can accelerate this process in younger women. What is low ovarian reserve and how does it affect fertility? Ovarian reserve measures how many viable eggs (oocytes) you have. We are born with a limited number and, over time, both quantity and quality decline. When the antral follicles detected by ultrasound are few and the antimüllerian hormone (AMH) in blood is low, the chances of conceiving naturally decrease and assisted reproduction may be necessary. Why is ovarian reserve important for conception? Knowing your ovarian reserve helps you plan your path to motherhood or fatherhood more effectively. A healthy reserve generally responds well to stimulation treatments, producing more mature eggs for fertilization, whether naturally or via in vitro fertilization, and improves successful pregnancy rates. What causes low ovarian reserve? Some factors can accelerate egg loss: Advanced age: After 35, egg quality and quantity decline more rapidly. Genetic factors: FMR1 gene premutations or premature ovarian insufficiency reduce reserve. Medical treatments: Chemotherapy or pelvic radiation can damage the ovaries. Ovarian surgery: Removing cysts or endometriomas removes healthy follicles. Autoimmune diseases: Lupus or thyroid disorders affect ovarian function. How is low ovarian reserve diagnosed? The following are used to confirm this diagnosis: Hormonal tests: FSH >10 IU/L on day 3 of the cycle or AMH

Fertility is a journey full of nuances where weight plays a very important role. Both low weight and excess kilos can influence the ability to conceive and the course of pregnancy. Here we explain in simple terms how weight affects fertility and what actions you can take. How does low weight affect fertility? When your BMI is below 18.5 kg/m², the body lacks sufficient energy and the hypothalamic-pituitary-ovarian axis reduces the release of GnRH, estrogen, and progesterone. This can cause irregular cycles (oligomenorrhea) or absence of menstruation (amenorrhea), making ovulation difficult. Additionally, the lack of key nutrients such as iron, omega-3, vitamins B12 and D can affect oocyte quality and uterine receptivity. If you become pregnant with low weight, the risk of preterm birth and a baby weighing less than 2,500 g increases. Avoid self-medication and always consult a professional. How does overweight influence fertility? With a BMI ≥30 kg/m², in women insulin resistance, hyperandrogenism, and ovulatory dysfunction increase, favoring conditions such as PCOS and thyroid problems. During pregnancy, the risk of gestational diabetes, preeclampsia, and obstetric complications rises. In men, excess fat raises scrotal temperature and converts more testosterone into estrogen, reducing sperm count and quality. Research shows increased sperm DNA fragmentation and morphological alterations. Weight management strategies to improve fertility Balanced diet Include fruits, vegetables, lean proteins, healthy fats (avocado, olive oil), and complex carbohydrates (oats, quinoa). Limit ultra-processed foods and refined sugars. Before supplementing or taking medication, consult a reproductive specialist. Moderate exercise Walking 30 minutes a day, swimming, or practicing yoga helps improve insulin sensitivity and cardiovascular health without stressing the reproductive axis. Avoid excessive training that elevates cortisol and affects ovulation. Specialist support An assisted reproduction team will offer you a personalized plan based on your history, lab tests, and lifestyle. With metabolic evaluation, nutritional advice, and, if necessary, hormonal treatment, your chances of conceiving are optimized. When to seek medical help? If after 6–12 months of dietary and exercise changes you haven’t achieved pregnancy, it’s time to see a specialist. Hormonal studies, ultrasounds, and semen analyses will be performed to identify the cause and define the best protocol (timed intercourse, intrauterine insemination, or IVF). Periodic follow-up allows for treatment adjustments and maximizes success. Frequently Asked Questions (FAQ) 1. What is the ideal BMI for conception? A BMI between 18.5 and 24.9 kg/m² offers a stable hormonal environment and increases the chances of pregnancy. But each person is different: age, genetics, and background have an impact, so a personalized evaluation is key. 2. Which nutrients should I prioritize if I’m underweight? Ensure iron (18 mg/day), omega-3 (EPA and DHA, 200–300 mg/day), vitamin D (600 IU/day), and protein (1.2 g/kg). Legumes, fatty fish, nuts, and fortified dairy will help. Consult a specialized nutritionist. 3. Can exercise be counterproductive? Moderate exercise (30–60 min, 3–5 days/week) is beneficial. Very high-intensity training or marathons can raise cortisol and disrupt the menstrual cycle. Combine light cardio, strength, and flexibility according to your tolerance and medical recommendations. 4. What treatment options are available if lifestyle changes don’t work? After 6–12 months without pregnancy, the specialist may suggest timed intercourse, intrauterine insemination, or IVF, depending on your diagnosis. Hormonal tests, ultrasounds, and semen analyses help design the most suitable plan. Sources Consulted American Society for Reproductive Medicine. (2020). Clinical Practice Guidelines on Obesity and Reproductive Health. DOI:10.1097/GRF.0000000000000547 Centers for Disease Control and Prevention. (2021). Pregnancy and Weight Gain. Retrieved from https://www.cdc.gov/reproductivehealth/maternalinfanthealth/pregnancy-weight-gain.htm MedlinePlus. (2023). Infertility. Retrieved from https://medlineplus.gov/infertility.html World Health Organization. (2018). WHO Guidelines on Nutritional Interventions for Reproductive Health. Retrieved from https://www.who.int/publications/i/item/9789241550438 We know that the path to parenthood can be challenging. You are not alone: rely on an assisted reproduction specialist to answer your questions and accompany you every step of the way.

Understanding the link between embryos and fertility In the world of fertility, embryos play an essential role. Understanding embryonic conditions is crucial for those seeking to conceive. This article dives into how embryos affect fertility and what we can learn from them. What is an embryo and its role in fertility? An embryo is the initial stage of development of a human being. After the fertilization of the egg by the sperm, a fascinating journey begins. During the first few days, the embryo divides and grows, preparing to implant in the uterus. This stage is critical, as a healthy embryo significantly increases the chances of a successful pregnancy. Embryo quality assessment Fertility specialists carefully examine embryos to determine their quality. They evaluate factors such as the rate of cell division the appearance and uniformity of the cells. A high-quality embryo is more likely to implant correctly and develop into a healthy fetus. Factors affecting embryo quality Several factors can influence the quality of the embryos. These include the age of the parents, especially the woman, as egg quality decreases with age. Other factors such as genetics, lifestyle, and certain medical conditions also play an important role. Advanced technologies in embryo evaluation With technological advances, it is now possible to perform more accurate evaluations of embryos. Techniques such as Preimplantation Genetic Diagnosis (PGD) allow embryos with genetic abnormalities to be identified before their transfer to the uterus. Impact of embryonic conditions on fertility treatments In treatments such as In Vitro Fertilization (IVF), selecting the best embryo is a critical step. Specialists strive to choose the embryo with the best chance of success to maximize pregnancy rates and minimize the risks of complications. Professional support and guidance For those on the path to creating a family, understanding and managing embryonic conditions can be overwhelming. This is where advice from fertility specialists is invaluable. These professionals not only provide technical support but also emotional support throughout the entire process. A hopeful path Although the path to conception can be full of challenges, understanding embryonic conditions and their impact on fertility is a step forward. With the right guidance and the support of advanced technologies, many people have achieved their dream of starting a family. If you are considering fertility treatments or have questions about embryonic conditions, do not hesitate to seek professional advice. Fertility experts are ready to guide and support you every step of this exciting and hopeful journey.

Embracing Hope in the Fertility Journey In a world where infertility affects a growing number of couples, assisted reproduction is presented as a solution full of hope. At Ingenes Fertility Institute in Mexico, we understand that this journey can be emotionally challenging, which is why we are dedicated to offering an empathetic and understanding path to parenthood. The Challenge of Infertility: A Reality for Many Couples Infertility is not only a medical challenge, but also an emotional and psychological one. It is estimated that one in six couples worldwide struggle with infertility. At Ingenes Fertility Institute in Mexico, we address these challenges with a comprehensive approach, offering not only medical treatments but also emotional support. Treatment Options in Assisted Reproduction At Ingenes Fertility Institute in Mexico, we offer a range of assisted reproduction treatments, including In Vitro Fertilization (IVF) and Intrauterine Insemination (IUI). Our goal is to provide the best treatment options tailored to each couple’s individual needs. Each treatment plan is designed considering each couple’s unique situation, ensuring they receive the best care and advice possible. The Assisted Reproduction Process at Ingenes The process begins with a thorough evaluation to identify the causes of infertility. This evaluation includes physical examinations, hormonal analyses, and imaging tests. Once the cause is identified, a personalized treatment plan is designed. Throughout the process, couples receive guidance and support, ensuring they understand each step and feel comfortable with their chosen treatment. The Role of Emotional and Psychological Support At Ingenes Fertility Institute in Mexico, we recognize that the journey to conception goes beyond physical appearance. Therefore, emotional and psychological support is a fundamental component of our services. We understand that every cycle, every test, and every wait can be loaded with intense emotions. Our emotional support team is available to help couples manage the stress and anxiety that often accompany these processes. We offer a safe space where couples can express their fears and hopes, helping them maintain a positive and resilient outlook. Technology and Experience at the Service of Fertility At Ingenes Fertility Institute in Mexico, we use the most advanced technology in the field of fertility. From the latest generation of IVF equipment to sophisticated monitoring and analysis systems, everything is aimed at maximizing the chances of success of each treatment. Our specialists are constantly up to date with the latest research and methods to ensure that each couple receives the best care possible. Commitment to the Individuality of Each Couple We recognize that each couple is unique, so we personalize each treatment. We not only consider the medical aspects of infertility but also each couple’s personal preferences, lifestyle, and emotional situation. This holistic approach allows us to tailor our treatments not only to achieve pregnancy but also to support couples throughout the process. Ingenes, More than a Fertility Clinic At Ingenes Fertility Institute in Mexico, we are more than a fertility clinic; We are a team dedicated to making dreams of fatherhood and motherhood come true. With a comprehensive approach, cutting-edge technology, and a strong commitment to each couple, we are here to guide and support you every step towards realizing your dream of having a baby at home.

The Artificial Intelligence (AI) revolution in the field of assisted reproduction is not only a future promise; It is a reality that is changing the way fertility treatments are approached. The application of Artificial Intelligence in this field is offering new perspectives and methods to improve the chances of success on the path to conception. AI Innovations in Embryo Selection Artificial Intelligence has shown impressive potential in improving embryo selection during In Vitro Fertilization treatments. Using advanced algorithms and machine learning, AI can analyze patterns and characteristics of embryos that might go unnoticed by the human eye. This includes the evaluation of embryo morphology, cell division rate, and other indicators of viability. Impact on Treatment Efficiency Ingenes’ Role in the Adoption of New Technologies At Ingenes Fertility Institute in Mexico, although we do not yet directly use Artificial Intelligence in our processes, we are committed to incorporating the latest innovations in the field of assisted reproduction. Our focus is always to provide the most advanced and effective care to our patients, and we are attentive to the evolution of Artificial Intelligence to integrate it at the right time, always to facilitate the path to motherhood and fatherhood. Long-Term Benefits of AI in Fertility Artificial Intelligence is not only intended to improve short-term outcomes in fertility treatments but also has the potential to provide valuable insights for future research. This could include developing more personalized treatments and advancing understanding of the underlying causes of infertility. The future of fertility treatments with the integration of Artificial Intelligence is promising. At Ingenes Fertility Institute in Mexico, although we are in the early stages of this transformation, we are preparing to embrace these emerging technologies. Our mission is to always be at the forefront, providing our patients with the best options available to make their desire to become parents come true.

Since their discovery in 1898, mycoplasmas have captured the attention of scientists and physicians alike. These tiny organisms are not only intriguing because of their nature, but also because they influence various diseases, some of which can be serious. In the field of fertility, its role is vital, a topic that at Ingenes we approach with attention and care. What are Mycoplasmas? Imagine mycoplasmas as tiny bacteria, very different from those we normally know. They are unique in their characteristics and their way of living. Although there are many varieties, some of these bacteria can coexist peacefully with us, while others can cause diseases in humans, animals, and even plants. Interestingly, these microorganisms are often found in newborns, but their presence decreases as they grow. Later, in adolescence and with the onset of sexual activity, species such as Ureaplasma urealyticum and M. hominis are usually found in the genital tract. The Impact on Fertility Mycoplasmas play a prominent role in certain reproductive diseases. For example, they have been associated with inflammation in the female reproductive system and other problems that can affect a woman’s ability to get pregnant or carry a pregnancy to term. They can influence fertility significantly, being a factor to consider in fertility treatments. Diagnosis and Treatments Mycoplasma infections are usually concentrated in the mucosal areas of the body and can manifest in various ways. Among them, are effects on the genitourinary tract and complications during pregnancy, such as spontaneous abortions or premature births. To diagnose it, doctors usually do cultures of different samples, such as blood or amniotic fluid. The Ingenes Approach At Ingenes Fertility Institute in Mexico, we are fully aware of how mycoplasmas can influence fertility. Our specialists perform a thorough evaluation to determine if these microorganisms are affecting your chances of conceiving and carrying a successful pregnancy. Our comprehensive approach includes advanced testing and personalized treatments to address any challenges related to these organisms. Prevention and Care An important part of our work at Ingenes is prevention. We advise our patients on how they can reduce the risk of mycoplasma infections, especially those who are trying to conceive. This can include everything from hygiene tips to recommendations on safe sexual practices. Treatment Alternatives at Ingenes If you are facing fertility problems related to mycoplasmas, all is not lost. At Ingenes Fertility Institute in Mexico, we offer a variety of treatments and alternatives to overcome these obstacles. From specific antibiotic treatments to assisted reproduction techniques such as IVF, we are equipped to help you on your path to motherhood. Mycoplasmas and their impact on fertility may seem complex, but at Ingenes we are prepared to help you understand and overcome these challenges. With the combination of cutting-edge technology, specialized knowledge, and a human approach, we accompany you every step of your journey towards conception and a healthy pregnancy.

The Mediterranean diet is famous for its health benefits and now also for its role in fertility. If you’re starting an in vitro fertilization (IVF) treatment, take note! A diet rich in fruits, vegetables, legumes, fish, and olive oil provides key nutrients that can increase your chances of success. What is the mediterranean diet and why does it matter in IVF? It’s based on fresh, natural foods: fruits, vegetables, whole grains, legumes, nuts, fish, and extra virgin olive oil. It includes dairy and lean meats in moderate portions and limits sugars and saturated fats. This way, you get antioxidants, omega-3 fatty acids, fiber, and micronutrients that improve egg quality, embryo development, and endometrial health. How does it improve egg and embryo quality? Studies show the Mediterranean diet: Reduces oxidative stress with antioxidants (vitamins C and E). Supports mitochondrial function with omega-3 fatty acids (EPA and DHA). Promotes healthy cell division thanks to folate. Key nutrients for fertility Antioxidants: vitamins C (ascorbic acid) and E (tocopherol). Omega-3: 1–2 g/day from fish or flaxseed. Folate: 400 µg/day from leafy greens and legumes. Monounsaturated fats: 20–40 mL/day of extra virgin olive oil. Incorporate the mediterranean diet today Choose seasonal produce, use 30–40 mL of extra virgin olive oil daily, and eat fish (salmon, sardines) 2–3 times a week (150 g per serving). Swap refined grains for whole grains—quinoa, farro, or whole wheat bread—snack on a handful (30 g) of nuts or seeds, and add 100 g of cooked legumes. A healthy, sustainable lifestyle Besides improving fertility, this diet protects your heart, regulates blood sugar, and reduces the risk of certain cancers. Prioritize plant-based foods, minimize processed items, and practice mindful eating. How Ingenes supports your nutrition At Ingenes we understand that nutrition is crucial in IVF. Our team guides you with personalized plans, integrating dietary counseling and advanced reproductive techniques. Discover the secret to successful IVF. The importance of balanced nutrition A well-balanced meal plan ensures essential macro and micronutrients for healthy eggs, quality embryos, and a receptive endometrium. More details at “The Importance of Nutrition in Fertility Treatment”. Practical tips for your reproductive health Fruits and vegetables: 5 servings daily. Lean proteins: 1.2–1.5 g/kg body weight (fish, poultry, legumes). Healthy fats: 20–35% of daily calories. Hydration: 2–2.5 L of water per day. Frequently Asked Questions 1. How long until I see changes? Following the diet for 3–6 months before IVF improves oocyte and embryo quality. Antioxidant levels rise in weeks, while lipid profiles and inflammatory markers stabilize over months. Consistency and gradual changes are key to regulating hormones, maintaining stable cycles, and optimizing endometrial receptivity. 2. What if I have dietary restrictions? The Mediterranean diet is flexible. If you’re vegan or vegetarian, increase legumes (100–150 g cooked) and nuts (30 g). For omega-3, use chia seeds or algae supplements. If lactose intolerant, choose fortified plant-based milks. Always consult your specialist or a dietitian. 3. What should I avoid in IVF? Limit red meat to under 300 g/week and avoid processed foods. Reduce sweets, refined grains, caffeine (≤200 mg/day), and alcohol. Opt for whole, colorful foods. 4. Why does olive oil help implantation? Extra virgin olive oil provides oleic acid and polyphenols that improve blood flow and reduce endometrial inflammation. With 20–40 mL daily, you promote a thicker, healthier uterine lining. Sources Consulted Martínez-González, M. A., & Estruch, R. (2021). Mediterranean diet, cardiovascular disease and mortality: a critical review. European Journal of Internal Medicine, 82, 1–3. https://doi.org/10.1016/j.ejim.2020.10.004 Gaskins, A. J., & Chavarro, J. E. (2018). Diet and Fertility: a review. American Journal of Obstetrics and Gynecology, 218(4), 379–389. https://doi.org/10.1016/j.ajog.2017.11.587 National Library of Medicine. (2022). Antioxidants and Reproductive Biology. MedlinePlus. https://medlineplus.gov/antioxidantsandreproductivehealth.html Thompson, J., & Hanna, J. (2020). Omega-3 Fatty Acids in Reproductive Health. Fertility and Sterility, 114(5), 987–993. https://doi.org/10.1016/j.fertnstert.2020.07.010 We know the journey to parenthood can be challenging. You’re not alone: every step counts. If you seek guidance and support, consult a fertility specialist for a personalized, professional plan to accompany you on this journey.

Stress is a key factor that can significantly impact fertility. At Ingenes Fertility Institute in Mexico, we understand the importance of addressing this aspect on the path to finding your baby. The Impact of Stress on Fertility Chronic stress affects both men and women. In women, it can influence the regularity of their menstrual cycles and ovulation, while in men, it can decrease sperm quality. The connection between stress and fertility is complex but real and significant. Stress During Fertility Treatments Couples undergoing fertility treatments often face high levels of stress due to the uncertainty, expectations, and emotional toll of the process. At Ingenes Fertility Institute in Mexico, we are aware of these challenges and offer support to manage them effectively. Symptoms of Stress to Take into Account Stress can manifest itself in a variety of ways, including anxiety, mood swings, sleep problems, and physical symptoms. Recognizing these symptoms is the first step to properly addressing them. Strategies to Manage Stress At Ingenes, we recommend several strategies to manage stress, such as relaxation techniques, regular exercise, a balanced diet, and psychological support. These strategies not only help reduce stress but also improve the chances of fertility treatment success. Emotional Support at Ingenes Our Emotional Support Health Unit offers specialized psychological support to help couples cope with the stress related to infertility and assisted reproduction treatments. This support is crucial to maintaining a positive attitude and improving your chances of success. Practical Tips to Reduce Stress We offer a range of practical tips to reduce stress, including the importance of establishing a support network, maintaining pleasurable activities, and practicing mindfulness and relaxation techniques. Impact of Stress on the Decision to Conceive We understand that stress can influence the decision to try to conceive. Our specialists are here to provide guidance and advice, ensuring each couple makes the best decisions for their unique situation. Ingenes’ Role in Your Fertility Journey At Ingenes, we not only focus on the medical aspects of fertility but also on the emotional well-being of our patients. Our goal is to provide a path to parenthood that is as calm and positive as possible. If you are facing fertility challenges and the stress associated with them, you are not alone. At Ingenes Fertility Institute in Mexico, we are committed to providing you with the support necessary to overcome these challenges. Contact us to learn more about how we can help you achieve your dream of becoming parents, in an environment of support and understanding.

The story of a 70-year-old woman who gave birth to twins has captured the world’s attention, challenging traditional perceptions about motherhood and age. At Ingenes Fertility Institute in Mexico, we understand the complexity and possibilities that modern fertility science offers those who dream of having a baby at home. The Extraordinary Case Recently, a 70-year-old woman became the mother of twins, a feat that defies all expectations. This case is not only a testament to human resilience but also an example of how assisted reproductive technology can create possibilities where none existed before. Fertility and Older Age Traditionally, age has been a limiting factor in female fertility. However, with advances in medical science, especially in the field of assisted reproduction, women in later stages of life are exploring motherhood. Advanced Technologies Several clinics use advanced technologies such as In Vitro Fertilization (IVF) and Intracytoplasmic Sperm Injection (ICSI). These treatments are especially significant for those facing age-related fertility challenges. Ethical and Medical Considerations Motherhood at an advanced age is not exempt from ethical and medical considerations. Several clinics approach these cases with a comprehensive approach, where they evaluate the risks and provide complete advice to guarantee the health of both the mother and the baby. Stories of Hope Each case is unique, and at Ingenes Fertility Institute in Mexico, we have witnessed many stories of hope and success. Our team of experts provides personalized support and guidance, helping couples and single women navigate the complex world of fertility. Comprehensive Support at Ingenes We understand that the path to motherhood can be challenging, especially for women and couples who have tried to have their babies at home. At Ingenes Fertility Institute in Mexico we offer comprehensive support that includes medical, emotional, and nutritional advice, ensuring that each patient receives the most complete care. The Future of Fertility Fertility science is constantly evolving. At Ingenes Fertility Institute in Mexico, we are committed to staying at the forefront of these innovations, providing our patients with the best options available. Motherhood is a personal and unique journey. At Ingenes Fertility Institute in Mexico, we are dedicated to making your dream of having a baby come true. If you are considering becoming a mother, we invite you to talk to our experts and explore the options that modern fertility science has for you. Contact us today and start your journey toward finding your baby!

What is an ectopic pregnancy and why does it happen? An ectopic pregnancy occurs when the embryo implants outside the uterus, almost always in the fallopian tubes, although it can also happen in the ovaries or the cervix. This occurs when something prevents the fertilized egg from reaching the uterus to grow as it should. Illustration of an ectopic pregnancy After experiencing an ectopic pregnancy, the most common question is: Can I get pregnant again? The good news is yes: around 40% of women achieve a subsequent pregnancy if the causes are properly identified and treated and with the guidance of an Assisted Reproduction specialist. How does a normal pregnancy occur, and what goes wrong in an ectopic? In a typical pregnancy: Ovaries: release a mature egg. Fallopian tubes: where the egg meets the sperm and fertilization occurs. Uterus: the ideal place for the embryo to implant and grow. If the tubes have adhesions, scars from infections (like chlamydia or gonorrhea), or prior surgery (for example, tubal ligation), the embryo cannot reach the uterus and implants elsewhere, causing an ectopic pregnancy. What are the symptoms of an ectopic pregnancy? From the start you may notice: Severe, constant pain in the lower abdomen, usually on one side. Light vaginal bleeding or brown spotting for several days. Nausea and dizziness, very similar to morning sickness. If the tube ruptures, you may experience: Intense, widespread abdominal pain. Rapid and weak pulse, cold and sweaty skin. Difficulty breathing or feeling faint. If you experience any of these symptoms, do not self-medicate and seek emergency medical attention. Who is at higher risk for an ectopic pregnancy? Common risk factors include: History of infections (chlamydia, gonorrhea). Endometriosis or pelvic adhesions. Tubal surgeries, including ligation or having only one tube. Smoking. Age 35 to 44 years. Congenital abnormalities in the fallopian tubes. How can I have a baby after an ectopic pregnancy? In vitro fertilization (IVF) is the safest route after an ectopic pregnancy because the egg and sperm unite in the laboratory, bypassing the tubes. The process includes: Ovarian stimulation with medication to obtain multiple eggs. Selection of the healthiest eggs and sperm. In vitro fertilization and embryo culture. Transfer of the highest-quality embryos to the uterus. Monitoring of hCG levels and embryonic development. Before making any decisions, consult an Assisted Reproduction specialist. They can design a tailored plan and increase your chances. At Ingenes we have an expert team in IVF and ectopic pregnancies to support you every step of the way. Frequently Asked Questions 1. Does the Risk of Another Ectopic Pregnancy Increase If I’ve Had One? The recurrence risk is 10–20%, depending on the health and function of your tubes. That’s why, before trying again, it’s advisable to perform an ultrasound and HSG to assess the tubes. If they’re damaged, IVF is the best option. 2. Can I Get Pregnant with Only One Tube? Yes. You retain a 50% chance of natural pregnancy thanks to the remaining ovary and tube. To improve success, IVF bypasses the tubes entirely. 3. Does IVF Hurt and What Are Its Risks? Egg retrieval is done under sedation, so there is no pain. Afterwards, you may experience mild discomfort and abdominal bloating. Risks are low: ovarian hyperstimulation (

At Ingenes we understand that every journey to motherhood or fatherhood is unique. Here we outline the main fertility treatments, how they work and how our cutting-edge technology and personalized protocols support you every step of the way. Artificial insemination: what it is and when to consider it Artificial insemination places washed sperm (0.5–1 mL) directly into the uterus near ovulation. It’s ideal if your partner has mild male infertility, no specific cause is found or there’s an issue with cervical mucus. At Ingenes we personalize hormonal stimulation and the timing of the procedure according to your cycle, increasing success rates without resorting to more invasive treatments. Never self-medicate: always consult a specialist. In Vitro Fertilization (IVF): What it involves and who benefits IVF combines eggs and sperm in the laboratory. After ovarian stimulation with 150–300 IU of gonadotropins daily, we retrieve mature oocytes, fertilize them in a culture medium and transfer the highest-quality embryo (8–10 cells on day 3 or blastocyst on day 5) into the uterus. It’s recommended for tubal factor, endometriosis, severe male infertility or if insemination has failed. Before starting, consult a Reproductive Medicine specialist. Prior recommendations: maintain your physical and emotional health. We help you prepare holistically. ICSI: When microinjection is the best solution ICSI injects a single sperm directly into the egg, ideal for severe oligozoospermia, azoospermia, low motility or previous fertilization failures. Our embryologists use high-precision micromanipulators to ensure each oocyte receives a viable sperm, overcoming male infertility barriers. Egg or Sperm Donation: When to consider it If gamete quality is suboptimal, a donor may be the solution. Candidates undergo genetic, infectious and psychological screening; we match donors by physical characteristics and medical history. We can use fresh or frozen embryos and our success rates exceed 60% per transfer. All under strict confidentiality and constant support. At Ingenes we combine experience and advanced technology to support you from the first consultation through embryo transfer and beyond. Our team provides attentive, dedicated care. Visit Your Journey to Motherhood to learn more and take the next step on your path to parenthood. Frequently Asked Questions What should I do before starting fertility treatments? Schedule a comprehensive evaluation: hormonal profile (FSH, LH, AMH) and pelvic ultrasound. Achieving a BMI of 18.5–24.9, quitting smoking and taking 400 µg of folic acid daily optimizes receptivity. Avoid self-medication and always consult your specialist. How do I know if I need ICSI instead of IVF? ICSI is recommended when concentration is under 5 million/mL, motility drops below 32% or after failed IVF cycles. Advanced semen analyses and genetic tests guide this decision along with your reproductive history. Can I use donor gametes if I have a genetic condition? Yes. If you carry hereditary mutations (BRCA1/2, cystic fibrosis), using a donor reduces risks. We conduct exhaustive genetic screening on donors and offer genetic counseling to help you make the best choice. What are the effects of ovarian stimulation? Common effects include bloating and mood changes. Rarely (1–2%) ovarian hyperstimulation syndrome may occur: abdominal pain, nausea and fluid retention. We monitor estradiol levels and follicles by ultrasound to adjust doses and prevent complications. Sources American Society for Reproductive Medicine. Committee Opinion No. 814. Fertility and Sterility, 118(2), 484–495 (2022). Practice Committee ASRM. Diagnostic Evaluation of the Infertile Female. Fertility and Sterility, 116(3), 673–684 (2021). MedlinePlus. Intrauterine insemination (2023). MedlinePlus. In vitro fertilization (2023). We are with you at every step. If you have doubts or need personalized guidance, consult a Reproductive Medicine specialist to guide and support you on this hopeful journey.

Egg retrieval, also known as follicular puncture, is an essential procedure in assisted reproduction. At Ingenes, this step is essential to achieve the dream of many couples: having a baby. But what exactly does this process entail and how is it carried out? Understanding Egg retrieval Egg retrieval is a technique used to extract eggs directly from a woman’s ovaries. This procedure is crucial in treatments such as In Vitro Fertilization (IVF) and is performed once the ovarian follicles have reached an adequate size and maturity, which is monitored through ultrasounds and hormonal analysis. The Puncture Procedure During the egg retrieval, the patient is under sedation to ensure her comfort. Using ultrasound technology, Ingenes doctors guide a thin needle through the vaginal wall to the ovaries, where mature eggs are carefully aspirated. This precise technique minimizes risk and ensures an effective collection of high-quality eggs. The Importance of Advanced Technology At Ingenes Fertility Institute in Mexico, we use the most advanced technology for egg retrieval. This not only increases the success rates of egg collection but also ensures maximum safety for our patients. The use of state-of-the-art equipment allows the procedure to be carried out with the greatest possible precision. Preparation and Recovery Preparation for egg retrieval includes a series of specific steps designed to maximize the chances of success. This includes controlled ovarian stimulation and close monitoring. Afterward, recovery is generally rapid, allowing most women to return to normal activities soon after. The Role of Puncture in In Vitro Fertilization Once the eggs are collected, the fertilization process begins in the laboratory. Here at Ingenes, each egg is carefully evaluated and selected for fertilization, either through traditional insemination or through techniques such as ICSI (Intracytoplasmic Sperm Injection). Security and Support at Ingenes At Ingenes, we understand that egg retrieval can be an exciting but stressful step for many couples. Therefore, we offer a supportive and advisory environment throughout the entire process, ensuring that each patient feels informed, comfortable, and safe. Beyond egg retrieval Egg retrieval is just one of many steps on the path to finding your baby. At Ingenes, we are committed to offering comprehensive and personalized treatment, which includes not only advanced medical procedures but also a holistic and empathetic approach to fertility. If you are considering fertility treatment, or if you want to know more about egg retrieval and how it can be part of your path to motherhood, we are here to help you. Contact us today to schedule your appointment and take the first step toward your dream of having your baby at home.

Endometriosis occurs when the tissue that normally lines the inside of the uterus appears elsewhere, such as on the ovaries or pelvic cavity. This abnormal growth can cause pelvic organs to stick together, leading to pain and impairing fertility. The condition can block the fallopian tubes or reduce ovarian reserve, making conception more difficult. For those wishing to become parents, In Vitro Fertilization (IVF) is often the best option. In IVF, eggs are fertilized in the lab and healthy embryos are transferred to the uterus. What is endometriosis and how does it affect your fertility? Endometriosis occurs when tissue similar to the uterine lining grows outside the uterus, on the ovaries, fallopian tubes, or peritoneum. Each menstrual cycle, this tissue bleeds without an exit, causing inflammation, scarring (adhesions), and pain. These adhesions can alter pelvic anatomy, block the tubes, and hinder ovulation, lowering the chances of natural conception. Studies show endometriosis can reduce both egg quality and quantity, as well as affect ovarian reserve markers like anti-Müllerian hormone (AMH). Early diagnosis and treatment improve outcomes. More details at Endometriosis: What is it and How Does it Impact Your Fertility? How to identify if you have endometriosis The most common symptoms are: Severe menstrual pain that limits daily activities. Chronic pelvic pain, sometimes radiating to the back or legs. Pain during intercourse. Irregular bleeding or spotting between periods. Fatigue and digestive issues like bloating or diarrhea. Diagnosis usually starts with a pelvic ultrasound, preferably transvaginal, and is confirmed by laparoscopy. At Ingenes, we choose ultrasound first to detect endometriomas, adhesions, and deep lesions with less invasiveness. Treatments to improve fertility in endometriosis Initial management may include anti-inflammatory medications for pain, hormonal therapy (e.g., GnRH agonists), and surgery to remove adhesions and restore pelvic anatomy. If pregnancy is the goal, Assisted Reproductive Technologies (ART) are often recommended post-surgery. IVF remains the most effective option in moderate to severe cases. Controlled ovarian stimulation protocols aim to retrieve multiple oocytes (8–15 mL of follicular fluid per follicle). Before starting, consult with a reproductive endocrinologist. Avoid self-medication. Lifestyle changes that support your fertility A diet rich in omega-3 fatty acids and antioxidants (fruits, vegetables) and low in red meat helps control inflammation. Regular low-impact exercise (yoga, swimming) improves pelvic circulation and relieves pain. Maintain a healthy BMI (18.5–24.9 kg/m²), avoid smoking, and limit alcohol. Stress-management techniques also benefit reproductive health. Frequently Asked Questions About Endometriosis and Fertility 1. How Does Endometriosis Stage Affect My Chances of Pregnancy? The American Society for Reproductive Medicine (ASRM) classification ranges from I to IV. Stages I–II have higher natural fertility, while stages III–IV involve more adhesions and ovarian damage. Each case is unique: large endometriomas (>3 cm) may require surgery or ART. 2. What Are the Risks of Surgery Before Trying to Conceive? Laparoscopy removes lesions and improves tubal mobility but can reduce ovarian reserve and create new adhesions. Discuss with a specialist to balance benefits and risks based on your reserve and goals. 3. What Is the IVF Success Rate in Endometriosis? It depends on age and severity. For women under 35 with mild to moderate endometriosis, the clinical pregnancy rate per cycle is around 40–50%. In severe cases, rates are lower, but combining surgery with personalized protocols improves outcomes. 4. Can Endometriosis or Its Progression Be Prevented? There’s no sure way to prevent it, but early detection and hormonal treatment can slow ectopic tissue growth. Maintaining an anti-inflammatory lifestyle (diet, exercise, stress management) helps control symptoms. If you experience severe pelvic pain or menstrual irregularities, see your gynecologist as soon as possible for timely evaluation. Sources American Society for Reproductive Medicine. (2012). Revised American Society for Reproductive Medicine classification of endometriosis: 1996. Fertility and Sterility, 67(5), 817–821. doi.org/10.1016/S0015-0282(16)62896-3 National Institute of Child Health and Human Development. (2020). Endometriosis. MedlinePlus. https://medlineplus.gov/endometriosis.html Giudice, L. C. (2010). Clinical practice. Endometriosis. The New England Journal of Medicine, 362(25), 2389–2398. doi.org/10.1056/NEJMcp1000274 Leonardi, M., et al. (2018). Transvaginal ultrasound mapping of deep endometriosis. Human Reproduction Update, 24(2), 234–250. doi.org/10.1093/humupd/dmx042 We understand how challenging this journey can be. You are not alone: seek professional support and consider guidance from a fertility specialist to increase your chances of achieving that long-awaited pregnancy.

“`html What is oocyte quality and why does it matter for your fertility? As years go by, especially after age 35, not only does the number of eggs in the ovaries decrease, but their quality does too. Oocyte quality reflects an egg’s ability to develop into a healthy embryo after fertilization. How do you know if your eggs are high quality? A high-quality egg has the correct number of chromosomes and the energy needed to grow and divide properly. If quality is low, the risk of chromosomal abnormalities and reproductive failure increases. Hormones like FSH and estradiol are measured to assess ovarian response. But the most accurate evaluation comes with an in vitro fertilization cycle and preimplantation genetic testing. Factors that can affect oocyte quality Besides age, there are other factors that can influence even young women: Genetic or immunological disorders Cancer treatments Tobacco use Endometriosis Obesity Polycystic ovary syndrome Options if oocyte quality is low There is no treatment that directly improves egg quality, but in vitro fertilization increases the chances of success. When your own eggs aren’t viable, egg donation is a highly effective option. At Ingenes, we combine cutting-edge technology with personalized care. We analyze the 10 causes of poor oocyte quality and support you emotionally throughout the process to give you confidence every step of the way. Ovarian reserve: what it is and how it’s measured Ovarian reserve is determined by the anti-Müllerian hormone (AMH) and the antral follicle count (AFC) via ultrasound. These values predict how many eggs you might retrieve and their potential quality. Knowing your reserve helps plan the best path to fulfill your desire to become a parent. How Ingenes supports you At Ingenes we offer: A team of assisted reproduction specialists Ongoing emotional support Protocols with preimplantation genetic testing Blastocyst-stage embryo transfer Remember: avoid self-medication. To protect your fertility, the best step is to see an assisted reproduction specialist. Frequently Asked Questions Can I Improve My Egg Quality with Lifestyle Changes? Eating an antioxidant-rich diet, maintaining a healthy weight (BMI 18.5–24.9), quitting smoking, and supplementing with folic acid, vitamin D (600 IU/day) and coenzyme Q10 (200–300 mg/day) can help. Relaxation techniques, yoga or therapy reduce stress and support a more balanced hormonal environment. These habits are supportive but don’t replace assisted reproduction treatment if ovarian reserve is low. When Should I Do Preimplantation Genetic Testing? PGT is recommended if you’ve had recurrent miscarriages, are over 35, or have genetic diseases in the family. Testing the embryo before transfer reduces the risk of chromosomal abnormalities and improves implantation rates. What Is Egg Donation for? Egg donation is an alternative when your own eggs aren’t viable. Eggs from young donors have better chromosomal quality and mitochondrial energy, increasing the chances of a successful pregnancy. At Ingenes we ensure rigorous selection, compatibility and emotional support. How Do Age and Hormones Affect Oocyte Quality? After 35, egg quantity and quality decline due to DNA wear and reduced mitochondrial function. High FSH levels (>10 mIU/ml on day 3) and low AMH (

Egg donation is a gift of hope for many couples facing fertility challenges. But did you know that the mother’s influence goes beyond genetics? Join us on this scientific and emotional journey. What is egg donation? Egg donation involves the use of donated eggs for conception, a valuable option for those who cannot use their eggs. But science shows us that the connection between mother and child is deeper than we imagine. Beyond Genes: The Influence of the Environment The uterine environment of the pregnant mother plays a crucial role in the development of the embryo. Factors such as nutrition, lifestyle, and even emotions can influence the growing baby, leaving a unique mark. Epigenetics in Egg Donation Epigenetics is the study of how the environment and experiences can alter gene expression. During egg donation, although the DNA comes from the donor, the surrogate mother can influence how this DNA is expressed. The Egg Donation Process at Ingenes At Ingenes, we understand the complexity and beauty of egg donation. Our process is not only guided by the latest science but also by compassion and comprehensive support at every step. The Emotional Impact of Egg Donation Egg donation is an emotional journey as much as a physical one. At Ingenes, we offer advice and support to navigate these issues, ensuring families feel complete and connected. Egg donation is a window to a world where science and love are intertwined. If you are considering this path to parenthood, Ingenes is here to guide you. Contact us to learn more about how we can help you build your family.

Exploring New Horizons in Playback Fertility science is opening doors to a world where the difficulties of starting a family become surmountable challenges. The latest advances in the reproductive field promise a future full of hope for those who long to have a child. The Science of Fertility Within Everyone’s Reach Fertility may seem like a complex topic but think of it as a puzzle that we are solving together. From known methods to innovations in genetics, science is working in your favor. Ingenes: Companions on Your Reproductive Journey At Ingenes Fertility Institute in Mexico, we are passionate about being at the forefront of reproductive science, transforming the latest research into effective and accessible treatments for you. Personalized Treatments for You Each person is unique, and at Ingenes Fertility Institute in Mexico we know it. That’s why we personalize each treatment, making sure it suits your specific needs. Advances That Inspire Hope Each discovery in fertility brings us closer to making your desire to have a child come true. We are here to support you, whether you are taking your first steps or have been on this path for some time. A Fertile and Hopeful Future Envision a future where reproductive challenges become success stories. With scientific advances, that future is possible. At Ingenes Fertility Institute in Mexico, we are committed to making it a reality for you. Commitment and Constant Support Our commitment at Ingenes Fertility Institute in Mexico is to accompany you at every stage of this exciting journey. From the first consultation to reaching your goal, we want to be those friends you can always trust. Are you ready to take this journey? Visit Ingenes and allow us to be part of your path to realizing your family. We are eager to support you in every step towards realizing your dream!

Fertilization with the ICSI method (intracytoplasmic sperm injection) offers higher success rates when one of the factors to address is teratozoospermia: we select a sperm with normal morphology and inject it directly into the egg, optimizing the chances of fertilization. What is teratozoospermia and why is its diagnosis important? Teratozoospermia is a medical term describing a high percentage of abnormally shaped sperm in semen. Teratozoospermia is defined when more than 96% of sperm have altered forms, reducing their motility and ability to penetrate the egg. What causes can lead to teratozoospermia? Semen quality can be affected by various factors: Diabetes mellitus Varicocele Vasectomy over 5 years ago Infections of the seminal tract Testicular problems or trauma Poor nutrition Smoking, alcohol, or drugs Exposure to insecticides and other toxins Advanced age (from 45 years, abnormal sperm increase) Cancer treatments (chemotherapy, radiotherapy) Recent fevers Excess heat (saunas, jacuzzis, vehicle seats) How is teratozoospermia diagnosed and classified? Diagnosis is made with a semen analysis after 3–7 days of abstinence: WHO: at least 4% normal sperm. Kruger: 4–15% normal = moderate teratozoospermia. Less than 4% normal = severe teratozoospermia. Normal sperm have an oval head of 5–6 µm × 2.5–3.5 µm and a flagellum of ~50 µm. What treatments exist to improve fertility? Artificial insemination: capacitated semen in the uterus. For moderate teratozoospermia and women under 35 years. In vitro fertilization (IVF): egg and sperm union in the lab. Recommended if the woman is over 35 years. ICSI: injection of a normal sperm into the egg. The option with the best rates in severe teratozoospermia. A healthy lifestyle enhances semen quality: balanced diet, essential amino acids (L-Carnitine), and antioxidants. Avoid self-medication. For more information on erectile dysfunction and fertility or male infertility and how to conceive a baby, visit our specialized articles. FAQ on teratozoospermia and fertility 1. Can teratozoospermia be corrected with lifestyle changes? In mild or moderate cases, improving habits (balanced diet, exercise, and reducing toxins) can increase the percentage of normal sperm. Antioxidants and L-Carnitine also help. If symptoms persist, consult a specialist. 2. Is ICSI safe for severe teratozoospermia? ICSI manually selects a sperm with good morphology and injects it into the egg, achieving high fertilization and pregnancy rates. Before the procedure, the doctor will assess your history and semen quality. 3. When can improvement be seen after treatment? The sperm production cycle lasts ~72 days, so changes in habits or treatments usually reflect in 2–3 months. Follow-up semen analyses help adjust the plan. 4. Does the man’s age influence the results? Men over 45 years have more abnormal sperm and lower motility. When planning IVF or ICSI, male age is considered to optimize the protocol. Sources consulted World Health Organization. (2021). WHO Laboratory Manual for the Examination and Processing of Human Semen (6th ed.). Cooper et al. (2010). WHO reference values for human semen characteristics. Human Reproduction Update, 16(3), 231–245. Carlsen et al. (1992). Evidence for decreasing quality of semen during past 50 years. BMJ, 305(6854), 609–613. MedlinePlus. (2022). Teratozoospermia. We know this journey can be challenging. Stay hopeful and remember each case is unique. Consulting an assisted reproduction specialist will give you the personalized guidance you need to increase your chances of success.

What is egg freezing and what is it for? Egg freezing is an assisted reproduction technique that helps you pause your biological clock. Your mature oocytes are retrieved and vitrified in liquid nitrogen at –196 °C, where they can be stored for up to 27 years. Avoid self-medicating without consulting a doctor, as each ovarian stimulation protocol is adjusted to your age, ovarian reserve, and health status. How to know if egg freezing is right for you? If you want to postpone motherhood without losing options, this technique is your ally. The first step is to see a specialist in Assisted Reproduction. With an anti-Müllerian hormone (AMH) test and an antral follicle count (AFC) via ultrasound, you’ll assess your ovarian reserve and confirm if it’s the ideal time. What medical reasons drive egg freezing? Besides personal reasons, there are medical situations that make this decision advisable: Chemotherapy or radiotherapy that damages ovarian reserve. Gender transition. Autoimmune diseases or gynecological oncology surgeries. In these cases, vitrifying your oocytes opens a door of hope for your family plans. Do you need a partner to freeze your eggs? No. Unlike embryos, only your oocytes are stored here. If in the future you decide to fertilize them and don’t have a partner, you can use certified donor sperm from a sperm bank. Egg freezing process step by step Ovarian stimulation with hormones (FSH and LH) in personalized doses (e.g., 150–300 IU/day). Ultrasound monitoring and estradiol (E2) measurement in pg/mL. Retrieval of mature oocytes via follicular puncture under sedation. Vitrification of each oocyte with cryoprotectant to prevent ice crystals. Storage in liquid nitrogen tanks (<–196 °C). With Ingenes, your oocytes are protected by a unique chain-of-custody system. Alternatives and next steps In addition to egg freezing, you can consider: Embryo vitrification. Ovarian tissue preservation. We recommend reading “Egg freezing: a strategic decision for your family’s future” to learn how these options fit your life plan. At Ingenes we provide guidance at every stage: freezing eggs means gaining time with warmth and security. Frequently Asked Questions (FAQ) 1. Does egg freezing guarantee a future pregnancy? Success rates vary based on your age at vitrification and oocyte quality. Women under 35 have over 90 % survival after thawing and 50–60 % pregnancy rates per cycle. However, factors like embryo implantation and endometrial receptivity also play a role. That’s why it’s essential to see an Assisted Reproduction specialist. 2. What risks does ovarian stimulation carry? The main risk is ovarian hyperstimulation syndrome (OHSS), with abdominal pain, bloating and, in severe cases, pleural effusion or ascites (< 2 % with modern protocols). Other effects include breast tenderness, mood changes, and mild discomfort during retrieval. At Ingenes we monitor you closely to ensure your well-being. 3. How long can eggs be stored? Vitrification keeps them viable for decades. There are cases of pregnancies after 27 years of storage. Legally, the limit depends on the country: in Mexico it’s up to 10 years, renewable with your consent. 4. Can I change my motherhood plans? Yes. You can use your oocytes with partner or donor sperm in IVF cycles whenever you choose. Also, if the law allows, you can transfer embryos to a gestational carrier. At Ingenes we support you with legal and psychological counseling every step of the way. Sources Consulted Practice Committee of the American Society for Reproductive Medicine. (2020). Mature oocyte cryopreservation: a guideline. Fertility and Sterility, 114(4), 767–781. https://doi.org/10.1016/j.fertnstert.2020.06.025 American College of Obstetricians and Gynecologists. (2018). Committee Opinion No. 745: Patient education and informed consent. Obstetrics & Gynecology, 131, e196–e205. https://doi.org/10.1097/AOG.0000000000002586 MedlinePlus. (2023). Egg freezing. Retrieved from https://medlineplus.gov/eggsfreezing.html European Society of Human Reproduction and Embryology. (2022). ESHRE Guideline: Oocyte preservation. Human Reproduction Open, 2022(1), hoac004. https://doi.org/10.1093/hropen/hoac004 We accompany you on your journey to motherhood and fatherhood. Don’t hesitate to seek the support of a fertility specialist to answer your questions and design a personalized plan. We’re with you!

Mira estos consejos para mejorar la fertilidad y tener más posibilidades de ser mamá. Recuerda que no estás sola en esto, estamos para ayudarte.