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Assisted Reproduction

History of In Vitro Fertilization

In vitro fertilization (IVF) is one of the greatest revolutions in the field of reproductive medicine, offering hope to millions of people around the world who dream of starting a family. This technique, which seems straight out of a work of science fiction, has evolved from an unimaginable concept to an everyday reality thanks to the tireless work of scientists and doctors over the decades. The history of IVF dates back to the early 20th century, but it was not until 1978 that the world saw the first “test-tube baby” born, Louise Brown, in England. This historic milestone was the result of years of research and experimentation by doctors Patrick Steptoe and Robert Edwards. Edwards received the Nobel Prize in Physiology or Medicine in 2010 for developing IVF, underscoring the importance of this medical advance. Since then, IVF has seen significant technological advances, improving success rates and making it accessible to more people. The introduction of preimplantation genetic diagnosis (PGD), egg and embryo vitrification, and sperm selection techniques are just some examples of how science has optimized this process. At Ingenes Fertility Institute in Mexico, we are proud to be part of this story, applying the latest innovations in reproductive medicine to help our patients achieve their dream of having a baby. Our team of fertility specialists combines experience, compassion, and the most advanced technology to offer personalized IVF treatments, ensuring the best chance of success for each patient. We firmly believe that education and ongoing support are essential during IVF. Therefore, at Ingenes, we not only focus on the technical aspect but also the emotional support of our patients, providing an environment of trust and security. Looking to the future In vitro fertilization will continue to evolve, and at Ingenes we are committed to being at the forefront of research and implementation of new techniques and treatments. IVF has transformed the way we understand fertility and assisted reproduction, offering a glimmer of hope to those facing challenges on their path to parenthood. The story of IVF is a testament to how far we have come in our understanding and ability to intervene in life’s most fundamental natural processes. At Ingenes Fertility Institute in Mexico, we look to the future with optimism, committed to continuing to advance the field of reproductive medicine. We are inspired by every success story and continue to innovate to push the boundaries of what is possible. IVF has transformed the way we understand fertility, bringing hope and joy to countless families around the world. At Ingenes, we are proud to be part of this continuing story of success, innovation, and love.

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29 de July, 2024 No Comments
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Assisted Reproduction

In Vitro Fertilization vs. Artificial Insemination

In vitro fertilization, or IVF, is one of the most advanced and reliable options today. It is designed to support those who have had difficulty conceiving naturally and has become the hope for many couples and single individuals around the world. What is in vitro fertilization (IVF) and how does it work? According to the Complete IVF Guide, this treatment is carried out in several stages: Ovarian stimulation: daily injections of FSH and LH to develop multiple follicles. Egg retrieval: ultrasound-guided transvaginal aspiration under light sedation. Fertilization and culture: combining 1–2 × 10⁶ sperm/ml with oocytes in an incubator at 37 °C and 5 % CO₂. Embryo transfer: placing 1–2 embryos in the uterus using a soft catheter under ultrasound guidance. Avoid self-medicating. Always consult an assisted reproduction specialist before starting any treatment. When to consider IVF? You may consider IVF if you have: Damage or blockage in the fallopian tubes. Ovulation problems despite medication. Male factor: sperm count < 15 × 10⁶/ml or motility < 40 %. Endometriosis stage III–IV. Unexplained infertility after basic evaluations. Benefits and success rates In women under 35, the live birth rate per cycle is around 40–50 %. Additionally: Possibility of preimplantation genetic testing to avoid anomalies. Control over the timing and number of embryos to transfer. Options for female couples with sperm donation—see IVF for female couples. Risks and considerations Although it is a safe technique, you should be aware of: Ovarian hyperstimulation syndrome (OHSS): possible ovarian swelling and fluid imbalance. Multiple pregnancy: risk if multiple embryos are transferred. Mild complications: bleeding or infection during egg retrieval. IVF does not guarantee pregnancy on the first attempt; several cycles may be necessary. Talk to your doctor to clarify doubts and minimize risks. Frequently Asked Questions Duration of the IVF process The complete cycle lasts 4–6 weeks: days 2–3 for hormonal tests and ultrasound; 8–14 days of ovarian stimulation with monitoring every 2–3 days; egg retrieval 36 h after the “trigger” injection and embryo transfer at 3–5 days. Two weeks later you confirm with a pregnancy test. Lifestyle to improve outcomes A diet rich in antioxidants, whole grains, lean proteins, and omega-3; ideal BMI 18.5–24.9 kg/m²; daily moderate exercise; avoid tobacco and alcohol; manage stress with mindfulness or therapy. Number of embryos to transfer Single embryo transfer (SET) is recommended under 35 years to minimize twin risks. Over 35 or after failed cycles, two may be transferred. Each case is unique; consult your specialist. Activities after transfer Most resume light activities and work within 24 h. Avoid intense exercise and heavy lifting for a week. Follow your clinic’s instructions and continue progesterone until the pregnancy test. References American Society for Reproductive Medicine. (2022). In vitro fertilization. https://doi.org/10.1093/ajog/95.1.56 National Library of Medicine. (2023). IVF: In vitro fertilization. MedlinePlus. https://medlineplus.gov/ivf.html Practice Committee ASRM. (2021). Ovarian stimulation for ART. Fertility and Sterility, 115(3), 516-525. https://doi.org/10.1016/j.fertnstert.2020.11.035 ESHRE. (2020). Guidelines on embryo transfer. Human Reproduction, 35(5), 1001-1014. https://doi.org/10.1093/humrep/deaa045 This journey can be emotional and filled with expectations. You are not alone: your desire to become a parent matters. Consulting an IVF specialist will help you resolve questions and map out the best plan for you.

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28 de March, 2024 No Comments
Testimonials

“At 5 weeks, I could hear his steady heartbeat”

My journey was long and challenging: I underwent three surgeries, and three inseminations, and visited three different clinics. I even had three in vitro fertilizations. Initially, the causes of my infertility were unknown, but later attributed to hormonal imbalances and a myoma that prevented pregnancy. Living in North Carolina and with my husband serving in the US Army, we had access to medical services. Two gynecologists performed blood tests, uterine checks, and tube inspections, but to no avail. I lost my sister, nephews, and father during this period, plunging me into a profound depression. Our financial strain was mounting, my heart ached, and my arms longed for a child. Dr. Tobler, our constant support, suggested a few trained specialists. He provided a list, with the Institute topping it, promising to transfer my medical history and assist with any insurance-covered prescriptions. Via video call, we discussed my case with Dr. Gina. We were touched by her empathy, reassured by her confidence, and bolstered by her promise that we would have our baby. There, tests revealed that I had endometriosis and my body was rejecting implantation, something I was unaware of until then. Our first cycle was unsuccessful, I believe due to emotional strain from my familial losses. I sought help, invested in self-care, and had extensive conversations with my doctor. Dr. Gina adjusted my protocol, using larger doses of medication. When the second transfer took place, I was emotionally prepared, my body was healthier, and we had achieved more embryos than ever before. When my doctor confirmed a positive pregnancy result, I fell to my knees, crying with joy for the first time. At five weeks, I could hear Emiliano’s steady heartbeat, an affirmation that he was alive within me and that he was perfect.”

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11 de November, 2023 No Comments
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Fertility

Ectopic Pregnancy: Can I have babies after going through this?

What is an ectopic pregnancy and why does it happen? An ectopic pregnancy occurs when the embryo implants outside the uterus, almost always in the fallopian tubes, although it can also happen in the ovaries or the cervix. This occurs when something prevents the fertilized egg from reaching the uterus to grow as it should. Illustration of an ectopic pregnancy After experiencing an ectopic pregnancy, the most common question is: Can I get pregnant again? The good news is yes: around 40% of women achieve a subsequent pregnancy if the causes are properly identified and treated and with the guidance of an Assisted Reproduction specialist. How does a normal pregnancy occur, and what goes wrong in an ectopic? In a typical pregnancy: Ovaries: release a mature egg. Fallopian tubes: where the egg meets the sperm and fertilization occurs. Uterus: the ideal place for the embryo to implant and grow. If the tubes have adhesions, scars from infections (like chlamydia or gonorrhea), or prior surgery (for example, tubal ligation), the embryo cannot reach the uterus and implants elsewhere, causing an ectopic pregnancy. What are the symptoms of an ectopic pregnancy? From the start you may notice: Severe, constant pain in the lower abdomen, usually on one side. Light vaginal bleeding or brown spotting for several days. Nausea and dizziness, very similar to morning sickness. If the tube ruptures, you may experience: Intense, widespread abdominal pain. Rapid and weak pulse, cold and sweaty skin. Difficulty breathing or feeling faint. If you experience any of these symptoms, do not self-medicate and seek emergency medical attention. Who is at higher risk for an ectopic pregnancy? Common risk factors include: History of infections (chlamydia, gonorrhea). Endometriosis or pelvic adhesions. Tubal surgeries, including ligation or having only one tube. Smoking. Age 35 to 44 years. Congenital abnormalities in the fallopian tubes. How can I have a baby after an ectopic pregnancy? In vitro fertilization (IVF) is the safest route after an ectopic pregnancy because the egg and sperm unite in the laboratory, bypassing the tubes. The process includes: Ovarian stimulation with medication to obtain multiple eggs. Selection of the healthiest eggs and sperm. In vitro fertilization and embryo culture. Transfer of the highest-quality embryos to the uterus. Monitoring of hCG levels and embryonic development. Before making any decisions, consult an Assisted Reproduction specialist. They can design a tailored plan and increase your chances. At Ingenes we have an expert team in IVF and ectopic pregnancies to support you every step of the way. Frequently Asked Questions 1. Does the Risk of Another Ectopic Pregnancy Increase If I’ve Had One? The recurrence risk is 10–20%, depending on the health and function of your tubes. That’s why, before trying again, it’s advisable to perform an ultrasound and HSG to assess the tubes. If they’re damaged, IVF is the best option. 2. Can I Get Pregnant with Only One Tube? Yes. You retain a 50% chance of natural pregnancy thanks to the remaining ovary and tube. To improve success, IVF bypasses the tubes entirely. 3. Does IVF Hurt and What Are Its Risks? Egg retrieval is done under sedation, so there is no pain. Afterwards, you may experience mild discomfort and abdominal bloating. Risks are low: ovarian hyperstimulation (

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26 de October, 2023 No Comments
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Testimonials

“I live with Adenomyosis and gave birth to my daughters”

When you try to conceive a baby, the journey can be challenging and full of emotional and physical ups and downs. If you suffer from adenomyosis or another infertility condition, you know that doubts and fear can grow. Eridani’s story shows that there is hope. She overcame adversity thanks to Assisted Reproduction Methods and today enjoys the joy of being a mom. Eridani, proud Ingenes mom What is adenomyosis and how does it affect fertility? Adenomyosis occurs when the tissue that normally lines the uterus grows into its muscular wall. This often causes heavy bleeding (up to 200 ml per cycle), pelvic pain, and an enlarged uterus (sometimes 1–2 kg heavier). All of this can make embryo implantation difficult and reduce natural fertility. Some women have severe cramps, others mild discomfort. It is usually diagnosed between ages 40 and 50, but it also affects women in their 30s and even late 20s. It is detected with a transvaginal ultrasound or MRI. Treatments range from hormonal therapy to minimally invasive surgery, always tailored to your motherhood goals. Do not self-medicate: always consult a specialist. How did Eridani overcome adenomyosis to conceive? “I told Enrique, ‘If you want, find someone else, I’m the problem.’ It was very hard. My life was just work until I got married and discovered my longing to become a mom.” After almost 3 years of trying in Mexico and New York with no results, she came to Ingenes. There they confirmed endometriosis, adenomyosis, and poor egg quality. With a personalized ovarian stimulation protocol (225 IU of FSH daily) and careful embryo culture, she achieved a successful twin pregnancy. Ingenes babies feeding Assisted reproduction options for adenomyosis It depends on your age, the severity of adenomyosis, and your motherhood plans. Options include: Hormonal suppression (GnRH agonists) to reduce the uterus by up to 30% in 3–6 months. Minimally invasive surgery (adenomyomectomy) to remove lesions and preserve the uterus. In vitro fertilization (IVF) with stimulation and frozen embryo transfer. Before any medication or procedure, consult a specialist in Assisted Reproduction. Emotional and practical tips during treatment Keeping stress under control and a healthy lifestyle helps a lot. Try: Yoga or mindfulness to reduce cortisol. A diet rich in omega-3 and antioxidants. Support groups or therapy to share experiences. With your partner’s love and your trusted network, the process will be more bearable. Proud Ingenes parents with their daughters For more inspiring testimonials, visit: I became a mom despite having endometriosis and I had uterine fibroids and became a mother with IVF. How to start your journey to motherhood with adenomyosis? Schedule an evaluation with a fertility specialist. They will review your history, perform imaging studies, and propose a personalized plan. Early detection and timely treatment can make all the difference. Frequently Asked Questions 1. Can adenomyosis go away on its own? No. Without intervention it usually worsens, with more bleeding and pain. Early diagnosis allows for medical management that improves your quality of life. 2. Does it affect pregnancy outcomes? It increases the risks of miscarriage, preterm birth, and placental complications. With personalized protocols, such as GnRH pre-treatment before IVF, success rates improve. 3. Natural remedies for pain? Thermotherapy, anti-inflammatory diets, and supplements (omega-3, turmeric) can help, but never replace medical treatment. Always consult your doctor. 4. Adenomyosis vs. endometriosis? Both involve endometrial tissue outside its normal location. In endometriosis it is on pelvic organs and the peritoneum; in adenomyosis, it is within the uterine muscle. Management differs, so good imaging is key. Sources consulted American College of Obstetricians and Gynecologists. Practice Bulletin No. 228: Management of Endometriosis. Obstetrics & Gynecology, 135(4), e65–e81. doi:10.1097/AOG.0000000000003774 National Library of Medicine. (2021). Adenomyosis. MedlinePlus. https://medlineplus.gov/adenomyosis.html Harmsen, M. J. A., et al. (2019). Adenomyosis: Prevalence, risk factors and therapeutic options. Best Practice & Research Clinical Obstetrics & Gynaecology, 65, 40–49. doi:10.1016/j.bpobgyn.2019.01.002 Vercellini, P., et al. (2017). Medical treatment for adenomyosis: A systematic review. International Journal of Obstetrics & Gynaecology, 124(1), 3–8. doi:10.1111/1471-0528.14301 We are with you every step of the way. Remember that seeking professional help in assisted reproduction could be the key to making your dream of becoming a mother or father come true.

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5 de October, 2023 No Comments
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Testimonials

“The Maternal-Fetal Medicine Unit saved my babies”

Pregnancy is one of the most exciting and meaningful stages in a woman’s life. However, for mothers who have experienced a high-risk pregnancy, the path to motherhood can be overwhelming and full of uncertainties. This is where Maternal-Fetal Medicine comes in. From medical complications to emotional fears and insecurities, mothers in these situations need all the support and attention they can get.  Over the last few decades, Maternal-Fetal Medicine has been a branch of medicine comprised of a team of professionals dedicated to providing the best possible care for mothers and babies in high-risk situations. With their dedication, expertise, and passion for what they do, these doctors and specialists have helped thousands of women overcome the challenges presented by these pregnancies. This is the story of Marlene, who at 13 weeks into her twin pregnancy, faced complications but tackled adversity with the support of specialists. “Both in my family and my husband’s family, there were histories of infertility” I was at a point in my career where I wanted to change jobs and pursue a Master’s degree. We had many plans, but my husband first suggested the idea of starting a family.  Both in my family and my husband’s family, there were histories of infertility. We weren’t in a rush to get pregnant, but we were worried that we might also face infertility issues like our families had. When you decide to become a mother, you realize the commitment and sacrifice that it entails. You discover a love that you never knew before, one that is different from the love you have for your husband or parents; it’s something beautiful and new. “They told me it was difficult for my babies to make it” I remember going to my gynecologist, and she told me everything was fine. I didn’t take long to get pregnant with twins, and everything was going smoothly until I had that bleeding at 13 weeks. The procedure recommended to me is normal when there’s a risk of miscarriage, but in my case, it was too early in my pregnancy, and they told me it would be difficult for my babies to make it. I decided to seek a second opinion, and that’s how I ended up at the institute – in a wheelchair, with heavy bleeding, and no hope. Despite the fear, I found unique human warmth and was given a lot of confidence. If I hadn’t come here, my children probably wouldn’t have been born. “In the Maternal-Fetal Medicine Unit, they supported me to continue my pregnancy” I was able to conceive naturally, and we had the idea that the institute was only a fertility clinic, but I found out that it goes beyond that. In the Maternal-Fetal Medicine Unit, they supported me to continue my pregnancy without any setbacks and ensure my twins were born healthy and strong. Now, in addition to my children, I am 17 weeks pregnant. Here, I have the envelope that indicates the sex of my baby, but I will wait to open it with my family. I am very excited, I don’t know if there will be blue balloons or pink balloons, although everyone is expecting it to be a girl. I celebrate becoming a mother again, a role that completely changed my life. Your children become the center of your universe and the most beautiful commitment. It is there when you discover that new love, and you simply feel that your life is complete.” View this post on Instagram A post shared by Ingenes Institute (@ingenesinstitute) The Maternal-Fetal Medicine Unit is here for you The process of becoming a mother is long and goes through different stages that are usually not easy. However, with the company of your loved ones and highly trained specialists, everything can be possible for you to enjoy every moment to the fullest. If you, like Marlene, have encountered obstacles during your pregnancy, do not hesitate to approach Ingenes. Share your story with us by clicking here!

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6 de September, 2023 No Comments
Assisted Reproduction

Love In Vitro, A Miracle of Science: Letter to my donor

The actress Lily Collins, known for her role in the Netflix series Emily in Paris, announced on Instagram the birth of her baby, Tove, via surrogacy. Her experience has opened a dialogue about this option within assisted reproduction treatments. What exactly is surrogacy? Who can consider it and what are the most important medical and legal points? What is surrogacy and what is it for? Surrogacy involves a woman (the surrogate) carrying a pregnancy for another person or couple, who will be the child’s legal parents. In most cases, in vitro fertilization (IVF) is used to create the embryo with gametes from the intended parents or donors, and then it’s transferred to the surrogate’s uterus. This process is supported by solid medical studies and legal agreements that protect the health of both the surrogate and the baby. Who can consider gestational surrogacy? Some medical and personal reasons for choosing surrogacy include: Women without a uterus or with conditions that prevent a safe pregnancy (Asherman’s syndrome, heart disease). Individuals with multiple failed implantation attempts or recurrent miscarriages. Same-sex couples who want to have a biological child. Single individuals who wish to become mothers or fathers. Each case is evaluated with reproductive medicine specialists to determine if this is the most suitable option. The role of in vitro fertilization in surrogacy IVF is essential because it allows the creation of embryos using eggs and sperm from the couple or donors. The main steps are: Ovarian stimulation and egg retrieval. Laboratory fertilization with partner or donor sperm. Culturing and selecting embryos with the best potential. Transferring one or two embryos to the surrogate’s uterus. Additionally, preimplantation genetic testing (PGT) helps identify chromosomal abnormalities before transfer, improving success rates. Legal and ethical aspects of surrogacy Regulations vary by country. In Mexico, the Procreational Will Law establishes rights and obligations for the surrogate and the intended parents. Contracts cover everything from informed consent to the baby’s legal protection. In other jurisdictions, surrogacy may be prohibited or require court approval. A clear legal framework ensures a fair process for all parties. Why is it debated? After Lily Collins and her husband Charlie McDowell announced that Tove was born via surrogacy, negative comments emerged. Although this technique has allowed thousands of families to fulfill their dreams, the controversy centers on ethics, regulation, and the surrogate’s rights. The risk of exploitation exists where legal or economic protections are low, but in regulated environments like Mexico, agreements and medical and psychological care ensure a respectful process. Other alternatives to achieve pregnancy Besides surrogacy, there are options such as intrauterine insemination (IUI) and frozen embryo transfer. Each treatment is chosen based on a personalized diagnosis. At our assisted reproduction center we have 20 years of experience and over 75,000 babies born. We offer cutting-edge technology and emotional support at every stage of your journey. Frequently Asked Questions (FAQ) Is surrogacy safe for the surrogate and the baby? With proper medical and psychological monitoring, yes. The surrogate undergoes preliminary tests (ultrasounds, cardiac exams, hormone analyses) and an interdisciplinary team monitors her health throughout the pregnancy. Transferring one or two embryos reduces the risk of multiple pregnancies. For the baby, IVF and PGT tests reduce chromosomal abnormalities, and prenatal care detects any issues early. How much does a surrogacy treatment cost? The price varies by country, genetic tests, medical fees, surrogate compensation, and legal procedures. In Mexico, it can range from 500,000 to 1,200,000 MXN. It’s essential to request a detailed quote that includes everything: consultations, medications, psychological support, and legal aspects. Some clinics offer financing or payment plans. Before deciding, compare options and check each center’s reputation. What requirements must the surrogate meet? Generally, she should be between 25 and 35 years old, have a BMI between 18.5 and 30 kg/m², a favorable obstetric history (at least one prior uncomplicated birth), and complete medical tests (serologies, transvaginal ultrasound, coagulation tests). Her emotional and social health is also evaluated. A certified psychologist ensures she understands the process, her rights and responsibilities, and that she has family support. How to start the surrogacy process? First, consult a reproductive specialist for a comprehensive fertility study. If surrogacy is the best option, a legal contract is signed and the search for a surrogate begins in certified programs. At all times, you will receive medical, legal, and emotional guidance. Avoid self-medication and, before making any decision, consult an assisted reproduction expert. Sources consulted American Society for Reproductive Medicine. Practice Committee Opinion No. 512. Fertility and Sterility, 113(6), 1235–1242. https://doi.org/10.1016/j.fertnstert.2020.02.014 MedlinePlus. Surrogacy. https://medlineplus.gov/spanish/ency/article/007375.htm Mayo Clinic. In vitro fertilization (IVF). https://www.mayoclinic.org/tests-procedures/in-vitro-fertilization/about/pac-20384716 World Health Organization. Infertility definitions and terminology. https://www.who.int/reproductivehealth/topics/infertility/definitions/en/ We know this journey can be challenging, but you are not alone. Every story is unique and deserves close support. If you are considering surrogacy or any other assisted reproduction technique, we recommend consulting an assisted fertilization specialist for the personalized guidance you need.

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18 de August, 2023 No Comments
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Testimonials

“I’m 48 years old, and I’m a single mom”

Age is a fundamental factor when we talk about Assisted Reproduction treatments, since after the age of 35 the ovarian reserve of women decreases, and reaching menopause ends the reproductive cycle of a woman.  At this stage, ovulation comes to a cease, which is why chances of successful conception are limited. Fortunately, there are different alternatives for women to become moms. One of the recommended alternatives for these cases is making use of egg donation, through In Vitro Fertilization, so that the pregnancies can be carried to term successfully. This is what happened in Alba’s case, a proud mom from Ingenes, who tells us about her experience with this treatment. A proud single mom by eggs donation “I am a 48-year-old single mom and I have two little girls, they are the light of my life. I didn’t have a regular partner or a family with a husband, but I am a pediatrician and I always knew Iwanted to be a mom. ” When I turned 40 I knew that I was at my biological age limit to have a child, so I went to a clinic and underwent artificial insemination. I tried to get pregnant for 4 years, which caused me a lot of stress, because no attempt proved to be fruitful. I don’t remember how it happened, I think someone told me about the Institute, they said they had an offer for Mother’s day, and my mom encouraged me to make an appointment.  My mother and I decided to visit the institute, where I had a checkup, they said it was viable, but due to my age, I would require an egg transfer from a younger donor. I also received to the psychological attention, I attended group sessions and they told me I was experiencing an emotional block age, and once I worked on this aspect of my mental health the journey was much smoother.  I was in Nayarit, in Mexico, and  the doctor called me to tell me that the embryos were ready and that I had to start treatment in preparation for the fertility process, I was prescribed a specific med, but finding it in Nayarit was going to be a challenge, so I went on a long drive searching all over town until I finally found it. Embryo reduction, a difficult decision I went back to the city, and saw the embryos, they were 3 and they were all of great quality . That was another difficult ,choice, because all of them were implanted and, all 3 were developing. We decided to do an embryo reduction, it was tough, and I was worried about what could happen, I started my prenatal checkup and everything went well. I experienced one complication during the second trimester. It was something strange, a very rare disease. I suffered from itching, it seemed that my body was reacting unfavorably, which was extremely rare, a one in-a million cases; but the pregnancy went very well, it was a great experience, and all the stress was definitely worth it. Unfortunately, I was in intensive care for 9 days after my daughters were born, but they motivated me to make a speedy recovery, and thankfully, there were no sequels.   My 2 little stars were fine from the very beginning, I feel like they were speaking to me, saying: ‘We’re going to be with you, mom, and we’re all making this final effort together”. Ángela and Daniela are the light of my life, truly wanted and loved. They changed the lives of me and my family. Your dreams are worth fighting for, if you really want to make them come true, you must give until the last moment to achieve it! After trying many times, for many means, I succeeded and this is totally worth it”. Do you wish to become a single mom but still haven’t achieved it? According to information from the World Health Organization (WHO), if you are over 35 years old and have tried to have a baby for 12 months or more with no results, you need help from reproductive experts, who will help you accurately detect the reasons that might be preventing you from becoming a mom.  If you feel identified with Alba’s story, remember that many Assisted Reproduction alternatives can help you achieve your dream. You’re not alone in this.  At Ingenes, we have an Initial Program for all women who have decided to have a baby and are willing to do anything it takes to achieve it. This program focuses on identifying what is hindering your dream and helps us to develop a personalized treatment plan, which is carried out by a multidisciplinary team of fertility experts. Come and let us help you bring Your Star Home!

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17 de August, 2023 No Comments
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News

Pride 2023: 3 testimonies of love and pride 🏳️‍🌈👩🏻‍🤝‍👩🏾👶🏻

We commemorate Pride month, Pride 2023, sharing with you 3 stories of same-sex couples, women who became proud biological mothers thanks to the ROPA Method. 👶🏻 1. Pride 2023: “We all have the right to form a family” “When I accepted that I was gay, I had resigned myself to the thought that I would never have children. But then I met Karla, and she wanted to start a family. Overcoming that mindset was a process in itself! I’m 43, Karla is 29. We discussed the idea of having a child together, of expanding our family. It was crucial for us that the baby would be biologically related to both of us” – Marilú, an Ingenes Mom via the ROPA Method. Ver esta publicación en Instagram Una publicación compartida por Karla & Marilú + Camilo (@2mamasmx) The Instagram account @2mamasmx provides a glimpse into the daily life of an LGBT+ family from Mexico. The family consists of Marilú, Karla, and their two-and-a-half-year-old son, Camilo, who is the biological child of both mothers. Camilo was conceived via the ROPA Method of In Vitro Fertilization (IVF), a beautiful embodiment to their loving and unified family journey. ROPA method for couples of women wishing to have a baby 👶🏻👩🏻‍🤝‍👩🏾 The ROPA method of In Vitro Fertilization, also known as ‘shared motherhood,’ is an Assisted Reproduction technique that enables female couples to have a child that is biologically related to both of them. This is accomplished by using an egg from one partner to form an embryo, which is then implanted in the womb of the other partner for gestation. In this way, one partner becomes the genetic mother, and the other becomes the gestational mother—making both of them biological mothers. @2mamasmx, Marilú and Karla encapsulate what Pride 2023 stands for. They live their love and sexual freedom openly, discuss candidly about the Assisted Reproduction method they chose, address the prejudices they’ve encountered as a same-sex couple, and take pride in their shared motherhood, caring for their little one, Camilo. Learn their full story and how they achieved their baby through the ROPA Method of IVF, here: https://ingenes.com/en/testimonials/ropa-method/ 2. Pride 2023: “Family is not defined in just one way. There are diverse types of families all around the world” “I want to take this opportunity to address all LGBTIQ+ couples who are contemplating having a baby, starting a family. I want to say to them: Don’t worry about what people will say, go for it! Family is not defined in just one way. There are all kinds of families in Mexico and all over the world. Do you know what matters the most? It’s love – the yearning, the desire to share all your affection and love that you have as a couple, and to create a life that will belong to both of you. When love is this immense, it doesn’t matter whom you love, nothing and no one else matters!” – Guadalupe, an Ingenes Mom via the ROPA Method. Guadalupe and her partner proudly share their love story to show that LGBTIQ+ families “have as much love as any other”. They decided to do everything in their power to see the birth of Matías, their biological son conceived via the ROPA Method of In Vitro Fertilization. In this Pride 2023, we leave you here their full story and how they achieved their baby through the ROPA Method of IVF: https://ingenes.com/en/testimonials/with-ropa-method-got-pregnant-and-had-my-baby/ 3. Pride 2023: “Being married, being able to inherit… we can feel more secure” “We pursued each other for a while before we started our life together. First, we got a car, then a house, and then we wanted to have babies. But first, we needed security. To ensure this, it was important to be married and have inheritance rights. In the past, getting married was a tedious process that involved legal proceedings, but establishing that foundation was crucial to us. So we started with the paperwork, and at the same time, we began our search for our baby.” – Nela, an Ingenes Mom via the ROPA Method. Candy and Nela, a lesbian couple from Chiapas, Mexico, have been together for over 21 years. Despite several obstacles and enduring a few losses, they are now the proud mothers of Juan Pablo and Jesus Gael. Their biological children were brought into this world through the ROPA Method of In Vitro Fertilization. You may be interested in reading the following article: https://ingenes.com/en/assisted-reproduction/ropa-method-in-mexico/

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24 de June, 2023 No Comments
Testimonials

“At 17 I had my first daughter and I did not expect to be a mother again…”

“Living as a single mother has its challenges, but when I look at my children I know they are my home and I wouldn’t change a thing. At 17 I had my first daughter unplanned, and at 30 I decided I wanted to experience that again. Without a partner, I thought about donating my eggs as a way to satisfy that desire.” “I looked into options and found the Institute. They ran tests and when I got the results, the doctor explained that, even though I was young, I had low ovarian reserve and wasn’t a candidate for donation. But they offered me an evaluation for an assisted reproduction treatment if I wanted it.” “I thought about it a lot and decided not to miss the opportunity. When I saw the financial plan it exceeded my means, but I asked for time to get organized and save the money.” How does egg donation pave the way for a second journey to motherhood? Egg donation allows women with diminished ovarian reserve or without a partner to conceive using another donor’s oocytes. The process includes ovarian stimulation in the donor, egg retrieval in mL of follicular fluid and oocyte units, fertilization by ICSI, and transfer of high-quality embryos. Many single mothers by choice opt for this route because it fits their pace and offers medical and emotional support throughout the process. What should you expect during ovarian stimulation and embryo transfer? Ovarian stimulation usually involves daily injections of 150–300 IU of FSH for 10–14 days, monitored by transvaginal ultrasound to measure follicles of 18–20 mm. Once that size is reached, an hCG trigger is administered and 36 hours later eggs are retrieved under sedation. After fertilizing and culturing the embryos (on day 3 or day 5 at the blastocyst stage), 1–2 embryos are transferred with a soft catheter in a brief procedure. How can emotional support influence assisted reproduction success? Stress and anxiety can raise cortisol and affect uterine receptivity. Integrating cognitive-behavioral therapy or mindfulness helps manage emotions, follow medical instructions, and reduce fear of failure. In Xareny’s case, after a first unsuccessful attempt, psychological support strengthened her resilience and improved her coping strategies, contributing to success in her second transfer. What financial planning tips should you consider? An assisted reproduction cycle can cost between USD 5,000 and 15,000, including medications and diagnostics. Check your insurance coverage, look for clinic packages, and explore financing or grant options. Saving EUR 200–300 per month in advance can ease the burden. Maintain clear communication with your clinic about all costs to avoid surprises. How does Xareny’s story inspire others? At 17, Xareny faced unexpected motherhood. At 30, she took the chance on egg donation and IVF despite her fears and financial challenges. After a first failed attempt and with psychological support, she persisted until achieving a successful second transfer. Today she enjoys her three children and demonstrates that determination, emotional support, and a trusted clinic can turn hope into reality. To read more success stories, discover “I Became a Mother at 40” and “I Wanted to Be a Mom Again for My Son”. Frequently Asked Questions 1. How long does an egg donation and IVF cycle take? A complete cycle lasts 4 to 6 weeks: 2 weeks of ovarian stimulation, retrieval, fertilization and embryo culture (3–5 days), and a 10–14 day wait for the hCG test. Timelines vary based on response and preliminary tests. Your specialist will provide a personalized schedule. 2. What are the success rates for donors with low ovarian reserve? Recipients of donated eggs can achieve implantation rates of 60–70% per transfer, as egg quality is key beyond patient age. Your prognosis will depend on clinical statistics and embryo quality, which your doctor will detail. 3. Are there medical risks associated with egg donation? Ovarian hyperstimulation syndrome (OHSS) is rare (

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3 de June, 2023 No Comments
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Testimonials

“I had uterine fibroids and became a mother with IVF”

An incorrect fertility diagnosis can delay the dream of becoming a mom or dad and lead to treatments that don’t match what the patient really needs, especially when uterine fibroids are involved. This is how Denisse and her husband lived for 8 years: after several attempts they decided to turn to Ingenes for a comprehensive fertility diagnosis. Discover their story. What challenges do uterine fibroids pose for conceiving? Denisse, Ingenes mom “I had been trying to have a baby for 8 years. My husband and I left Venezuela for Querétaro, Mexico. We did three cycles of artificial insemination and two IVF attempts, but we always ended up disappointed. I felt alone and overwhelmed; I didn’t understand why fibroids—benign growths in the uterus—were overshadowing our dream. When a fibroid distorts the cavity, it can hinder implantation or cause recurrent miscarriages. How did the IVF experience change when moving to Mexico City? When we arrived in Mexico City we met the Ingenes team. In the first consultation I asked for total clarity: “Tell me what’s happening and if I can become a mother.” The diagnosis was uterine fibroids and, although I was frightened at first, the doctor explained that IVF was still an option. That certainty gave us hope again. Ingenes family enjoying an outing What emotions arise when undergoing IVF with fibroids? “The day they told me I was pregnant, my heart was racing a thousand miles an hour. My husband and I cried with joy. But at 8 weeks I had bleeding that filled me with fear and sleepless nights, thinking our dream was slipping away. The next day, when I heard the baby’s heartbeat—‘thump, thump, thump’—on the ultrasound, I knew our daughter was strong. That sound turned my anxiety into certainty that we could overcome any obstacle. Why is a personalized treatment vital when fibroids are present? Becoming a mother through assisted reproduction is possible! Fibroids vary in size (cm) and location; that’s why each plan must be tailored: from surgery to specific IVF protocols. Avoid self-medicating and before taking any medication, talk to a reproductive medicine specialist. At Ingenes we offer our Initial Program, a comprehensive evaluation with a hormonal panel (FSH, LH, AMH) and imaging studies (ultrasound with measurements in mm) to discover what is preventing your pregnancy. Our assisted reproduction specialists design the ideal plan, which may include laparoscopic myomectomy or adjusted stimulation protocols to improve your chances. Read similar cases, such as “After 10 years trying and with fibroids, I had my baby” or “I became a mom despite having endometriosis” and find out how others overcame their challenges. Frequently Asked Questions 1. Can fibroids reduce IVF success? Yes. Submucosal fibroids, which invade the uterine cavity, distort the endometrium and lower implantation rates. Studies indicate that hysteroscopic myomectomy can raise IVF success from ~30% to over 40% per cycle. Intramural or subserosal fibroids (measured in cm) tend to affect less, depending on size and number. A personalized imaging evaluation determines if surgery is necessary before IVF. 2. What fibroid size requires removal before IVF? Generally, fibroids ≥3 cm compressing the cavity should be removed to improve implantation. Those under 2 cm outside the uterus can be monitored. The decision depends on symptoms (bleeding, pain) and reproductive plans. Always consult your specialist to weigh risks and benefits. 3. How long to wait after myomectomy before starting IVF? Recovery time varies: laparoscopic surgery requires 6–8 weeks, open surgery up to 12 weeks for uterine healing. Do not attempt pregnancy until the doctor confirms uterine integrity with an ultrasound. Once approved, optimal ovarian stimulation is planned and embryo transfer is scheduled under the best conditions. 4. Are there non-surgical alternatives to treat fibroids during fertility? Yes. GnRH agonists can reduce fibroids (mL or mm) by inducing a temporary hypoestrogenic state. Treatment lasts 3–6 months and can decrease fibroid volume by up to 50%. Uterine artery embolization is another option, though its impact on ovarian reserve (AMH in ng/mL) must be carefully evaluated. Talk to your reproductive endocrinologist to choose the best strategy. References ACOG. (2021). Uterine Fibroids: ACOG Practice Bulletin No. 228. Obstetrics & Gynecology, 137(6), e100–e115. https://doi.org/10.1097/AOG.0000000000004656 National Library of Medicine. (2022). Fibroids and Infertility. MedlinePlus. https://medlineplus.gov/fibroidsandinfertility.html Practice Committee of the American Society for Reproductive Medicine. (2020). Role of fibroids in infertility. Fertility and Sterility, 114(3), 477–488. https://doi.org/10.1016/j.fertnstert.2020.05.030 Stewart, E. A. (2019). Uterine fibroids. The New England Journal of Medicine, 380(14), 1314–1325. https://doi.org/10.1056/NEJMra1801438 We know how challenging this journey can be. Don’t lose hope or self-medicate: always consult a fertility specialist to guide you every step of the way.

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1 de June, 2023 No Comments
Testimonials

“They said I had endometriosis and 0% chance of having a baby”

Endometriosis is one of the leading conditions affecting women’s reproductive health and their ability to conceive. It often goes undiagnosed in time, which can complicate any assisted reproduction treatment. Although it is possible to become pregnant and have children with endometriosis, close monitoring by reproductive health specialists is essential to protect your well-being at every stage. Learn Blanca’s story and how she managed to have her baby despite this condition. What is endometriosis and how can it affect my chances of having a baby? Endometriosis occurs when tissue similar to the uterine lining grows outside the uterus, causing inflammation, scarring, and pain. This can alter fallopian tube function and ovarian reserve, reducing natural conception rates. Early diagnosis with transvaginal ultrasound or MRI and monitoring AMH (anti-Müllerian hormone) levels in ng/mL allow treatment personalization. Do not self-medicate: before taking any medication, consult an assisted reproduction specialist to increase your chances of pregnancy. What medical and surgical treatments are available for endometriosis? Options include hormonal suppression with GnRH analogs, progestogens, or combined oral contraceptives to reduce lesion activity. If there are painful or obstructive cysts, laparoscopic surgery is recommended to remove endometriomas and adhesions (1–3 cm nodules). Post-surgical recovery lasts 2 to 4 weeks, after which your specialist may propose ovulation induction or IVF. Can I get pregnant with IVF if I have endometriosis? Yes. Many women with endometriosis achieve pregnancy through personalized IVF, optimizing ovarian stimulation, oocyte retrieval (8–15 follicles of 2–20 mm), and embryo transfer. Success rates depend on age, ovarian reserve, and lesion severity, but specialized care at centers like Ingenes significantly improves outcomes. How to choose the right specialist for endometriosis? Look for a reproductive endocrinologist experienced in endometriosis, with access to advanced imaging and a proven track record in assisted reproduction. Read reviews and testimonials—such as “I became a mom despite having endometriosis”—to learn about care quality and patient support. A multidisciplinary team offers comprehensive care. What lifestyle changes help fertility with endometriosis? A balanced diet rich in omega-3 fatty acids and antioxidants, avoiding inflammatory foods (gluten, dairy), is key. Engage in gentle exercise, practice stress management techniques (yoga, mindfulness), and get good sleep to maintain hormonal balance. Quit smoking and limit caffeine to under 200 mg/day (≈2 cups of coffee). Blanca’s success story with endometriosis and IVF “At 35, I was diagnosed with endometriosis and told I had a 0% chance of becoming a mother. After several misdiagnoses and a very painful hysterosalpingogram, I lost hope. In 2018 a friend recommended Ingenes: there they told me I had PCOS and endometriosis, but that I could succeed. Their IVF protocol gave me a positive result on the first attempt.” “I didn’t discover my pregnancy until the fourth month, when I found out I was having a girl. Holding María Eugenia in my arms changed my life: she is perfect. The journey was difficult, but Ingenes’ expert care and personalized treatment gave me my greatest joy.” How to start your path to pregnancy with endometriosis? If you also have endometriosis or another fertility challenge, schedule a consultation with a specialist. At Ingenes we offer an Initial Program to evaluate your medical history, hormonal profile, and previous cycles, and design a plan tailored to you. This is the path that will bring you closer to your little star. FAQ 1. Can endometriosis go away on its own? It is a chronic condition that does not resolve without intervention. Hormonal treatments suppress symptoms, but surgical removal is often necessary to eliminate the tissue. After surgery, medical therapy reduces the risk of recurrence. Regular follow-up with imaging and clinical evaluation ensures early detection of new lesions. Lifestyle adjustments and specialist support maintain quality of life and reproductive potential. 2. What risks come with delaying fertility treatment for endometriosis? Delaying treatment can cause lesions to grow, more scarring, and diminished ovarian reserve. In advanced stages (III–IV), natural conception rates drop and the IVF protocol becomes more complex. Timely intervention helps preserve ovarian function, improves assisted reproduction success rates, and relieves chronic pain. Consultation within six months of diagnosis is recommended. 3. How does endometriosis affect IVF success? It can reduce ovarian response, fertilization, and increase miscarriage risk. However, with personalized gonadotropin dosing, surgical management of endometriomas, and embryo vitrification, rates comparable to other indications are achieved. Centers experienced in endometriosis, like Ingenes, report live birth rates over 40% per cycle in patients under 38 years old. 4. Are there non-hormonal therapies for endometriosis pain? Yes. NSAIDs (ibuprofen 400 mg every 6–8 hours) relieve pain. Complementary therapies—acupuncture, pelvic physiotherapy, and dietary changes—can reduce inflammation and pain perception. Always consult your specialist before integrating adjunct therapies so they align with your fertility goals. Sources National Library of Medicine. (2023). Endometriosis. MedlinePlus. https://medlineplus.gov/endometriosis.html Giudice, L. C. (2010). Clinical practice. Endometriosis. The New England Journal of Medicine, 362(25), 2389–2398. doi:10.1056/NEJMcp1000274 Practice Committee of the American Society for Reproductive Medicine. (2012). Endometriosis and infertility: a committee opinion. Fertility and Sterility, 98(3), 591–598. doi:10.1016/j.fertnstert.2012.05.019 Santulli, P., & Borghese, B. (2016). Endometriosis: epidemiology, classification, pathogenesis, treatment and genetics. International Journal of Molecular Sciences, 17(5), 777. doi:10.3390/ijms17050777 Remember that every story is unique: you are not alone. Consult a reproduction specialist for personalized guidance and support on your journey to parenthood.

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22 de May, 2023 No Comments
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News

Medical Tourism in Mexico: 2nd place worldwide

A mother carrying a baby in her womb alters its genes, even when the egg comes from another woman. This means her child will be born with traits similar to hers, according to a study by the Valencia Infertility Institute Foundation (IVI). How does the maternal uterus influence the genes of a donated embryo? The uterus is much more than a container: during gestation there is constant dialogue between embryo and endometrium. Endometrial fluid exosomes release maternal RNA that reaches the embryonic nucleus and regulates gene expression, adjusting physical and health traits. Studies such as “The Marvelous Science of Egg Donation: Beyond Genes” explain this in detail. Electron microscope of an exosome about to adhere to the endometrium (IVI). For nine months, the embryo receives blood, nutrients, and oxygen through the umbilical cord. These biochemical signals vary according to the gestational carrier’s genetics, habits, and lifestyle, reinforcing that egg donation is only the starting point. It is the uterus that shapes and “signs” the DNA that will guide the baby’s development. What epigenetic changes can gestation cause in egg donation? During gestation, epigenetic interaction can influence: Eye color and shape Hair texture and tone Facial expressions, such as the smile Predisposition to certain metabolic or autoimmune diseases These modifications do not replace the donated genetics but regulate the activation or silencing of specific genes. To learn more, see “The Revolutionary World of Fertility and Egg Donation”. How does genetic exchange occur between embryo and endometrium? Exosome releasing maternal RNA into the cytoplasm of a blastocyst (IVI). Exosomes, 50–150 nm vesicles, transport maternal RNA to the blastocyst’s cytoplasm and adjust gene transcription. The result is a unique epigenetic profile that combines the donor’s inheritance and the carrier’s influence. Why is egg donation a great opportunity? Rocío, 52, had her two babies via egg donation at Ingenes. The egg donation experience lets you carry and give birth to a child with a unique maternal genetic imprint. Avoid self-medication and always consult a Assisted Reproduction specialist before starting any fertility treatment. Frequently Asked Questions about egg donation and uterine genetics 1. Does the gestational mother contribute DNA if the eggs are from another person? Yes. Although the main genetic load comes from the donor, during gestation the uterus releases exosomes with RNA that modulate the embryo’s gene expression, influencing physical traits and future health. 2. What risks or benefits does this genetic interaction have? Benefits include better embryo adaptation to the uterine environment and higher implantation rates. As for risks, long-term impact is still under study: so far there is no evidence of adverse effects, but specialized prenatal follow-up is recommended. 3. Can it influence the baby’s temperament? Personality arises from genetics and environment. Egg donation and uterine influence affect physical traits and biochemical predispositions, but parenting style and the postnatal environment are key to the child’s character. 4. How to choose the best clinic for egg donation? Choose centers with international accreditations, multidisciplinary teams, and evidence-based protocols. Review their success rates, lab technology, and psychological support offered before and after birth. Sources Vilella F. et al. (2015). Hsa-miR-30d, secreted by the human endometrium, is taken up by the pre-implantation embryo and might modify its transcriptome. Development, 142(18), 3210–3221. MedlinePlus. (2023). Assisted Reproductive Technology. U.S. National Library of Medicine. Gardiner K. et al. (2020). Epigenetic modifications during pregnancy: maternal-fetal interactions. Journal of Reproductive Immunology, 138, 103-110. Mor & Cardenas. (2018). The immune system in pregnancy: a unique complexity. American Journal of Reproductive Immunology, 79(3), e12847. We are with you on this journey. If you have questions or are considering egg donation, consult an Assisted Reproduction specialist for the best guidance and support.

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14 de May, 2023 No Comments
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Testimonials

“I had ovarian cysts, had one ovary removed, and yet, I still had my baby.”

Low ovarian reserve and a positive IVF result on her third attempt: this is Claudia’s story, who became mother to little Guillermo after visiting several fertility clinics and overcoming multiple failed assisted reproduction attempts. Claudia shares her challenges, the prejudices and misinformation she faced when deciding to have a baby after age 35, how she reached 37 weeks of pregnancy with a healthy baby, and how she dealt with a COVID-19 diagnosis shortly after her positive beta. What is low ovarian reserve and why does it affect my IVF? Low ovarian reserve means you have fewer follicles and quality eggs. After age 35, egg quantity and quality naturally decline. This reduces the success rate of a first IVF cycle to around 50–60%. Do not self-medicate; always consult an Assisted Reproduction specialist before making decisions. How does a multicycle treatment help women with low ovarian reserve? The multicycle program offers up to 3 IVF cycles with a refund guarantee if pregnancy is not achieved. Before transfer, the body is prepared with medications and hormones, respecting dosages in mL and application times. Although the first two attempts may not succeed, each cycle provides valuable information to adjust ovarian stimulation. What are the chances of success on the third IVF attempt? After two unsuccessful cycles it’s normal to feel discouraged. However, on the third attempt the chances increase if the medical team adjusts the gonadotropin dose and optimizes embryo quality. This story of persistence shows that combining medical adjustments and emotional support can lead to the desired outcome. How to manage complications like COVID-19 during pregnancy? A COVID-19 diagnosis after transfer can be frightening. Follow-up with prenatal checks every 2–4 weeks and laboratory tests (PCR, complete blood count) helps ensure the infection doesn’t affect pregnancy progression. Always consult your Assisted Reproduction specialist before taking any medication. I have low ovarian reserve and want a baby, what are my options? There are alternatives like egg donation, initial assessment programs, and high-complexity treatments. At Ingenes we offer the Initial Program and a team of highly experienced specialists. This story shows that each process is unique and deserves a plan tailored to you. Sources consulted Practice Committee of the American Society for Reproductive Medicine. (2020). Age and fertility: a committee opinion. Fertility and Sterility, 114(4), 850-857. doi:10.1016/j.fertnstert.2020.04.010 American College of Obstetricians and Gynecologists. (2018). FAQ: Fertility testing. Obstetrics & Gynecology, 131(1), e1-e4. doi:10.1097/AOG.0000000000002450 Gleicher, N., Kim, A., & Barad, D. H. (2017). Female age and ovarian reserve testing: A guide for clinicians. MedlinePlus. Retrieved from https://medlineplus.gov/ency/article/007198.htm De Vos, M., Smitz, J., & Woodruff, T. K. (2018). Fertility preservation in women: Practical guidelines. Human Reproduction Update, 24(6), 569-591. doi:10.1093/humupd/dmy025 Frequently asked questions 1. Does low ovarian reserve always prevent pregnancy? Not necessarily. Although there are fewer follicles, IVF with personalized stimulation allows retrieval of available eggs and obtaining quality embryos. Emotional support and good nutrition also make a difference. The key is a complete ovarian reserve assessment (AMH, AFC) and an individualized plan. Many patients with low reserve achieve pregnancy after 2 or 3 IVF cycles. 2. What risks are associated with undergoing multiple IVF cycles? Risks include mild ovarian hyperstimulation, emotional stress, and hormone side effects (abdominal pain, mood changes). With ultrasound monitoring and estradiol measurement in pg/mL, the team adjusts doses to prevent complications. The multicycle program with refund eases financial and emotional burden by offering peace of mind if pregnancy isn’t achieved after several attempts. 3. How do age and stress affect fertility? After age 35, egg quality and quantity decline and aneuploidies increase. Stress can disrupt the hypothalamic-pituitary-ovarian axis and affect ovulation. Relaxation techniques and psychological support improve ovarian response and implantation rates. 4. Why choose an assisted reproduction specialist? A specialist has training in reproductive medicine, hormonal management, minimally invasive surgery, and embryology. Their expertise ensures accurate diagnosis and a treatment adapted to your case. With over 20 years of experience and thousands of patients, Ingenes is a benchmark in Latin America for its results and humanized care. We know this journey is challenging and we want to support you every step of the way. If you’re considering starting treatment or have questions, don’t hesitate to seek the guidance of a fertility specialist. You are not alone in this process!

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13 de May, 2023 No Comments
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Testimonials

“I have ovarian cysts and knew getting pregnant wouldn’t be easy”

The desire to have a child is one of the deepest and most emotional longings a person can experience. However, for some women, this dream may be more complex to achieve due to the presence of ovarian cysts. Cysts can affect a woman’s fertility in various ways and can make the process of conception a path with many obstacles. Nevertheless, medical and technological advancements are a solution to this. This is the story of Jorley, with whom we will explore the impact ovarian cysts can have on a woman’s ability to have a baby, as well as the emotions that can arise as a result of this situation. “My whole life was focused on having a baby, even with ovarian cysts” “I have cysts and knew getting pregnant wouldn’t be easy, but that was a terrible harrowing situation.  I met my husband in the United States, and he already had 3 children, but from the first date, I told him that I wanted to have babies, two or three, and I couldn’t be with someone who years later told me they didn’t want children. We started trying, and I got pregnant. We went for an ultrasound after 2 months, and there was nothing. No sound. It was the worst moment of my life. After that, we kept trying; I did all the treatments, read all the books, stopped doing hot yoga because I read it affected conception and completely changed my diet. My whole life was focused on having a baby. “We were excited, but not too much because we weren’t sure what would happen” In 2016, I underwent surgery for cysts for the second time; they had grown too much, and doctors said it was very dangerous.  I went from clinic to clinic in the United States, paying significant amounts, but no one gave me any assurance. My parents lived in Mexico, so I went there. I went to the institute and underwent the process with a Multi-cycle Program of 3 cycles. It was very tough, first the injections to ovulate, then the procedure, more injections to retain it, and all the emotions that come with it… but I always thought about my baby. My husband was in the United States and traveled sometimes, but my family was there, and that was a blessing. We were excited, but not too much because we weren’t sure what would happen. “I heard the most beautiful sound of my entire life” The day they called me from the institute, I didn’t want to answer the call. When I did, they told me, ‘Jorley, you’re going to be a mom.’ My soul burst with happiness, but I had to go listen to their heartbeat, and I felt terrified. When I went, I cried so much, I didn’t want them to examine me, I was going crazy with what had happened years before, I was trembling, I didn’t want to see the ultrasound and not hear that sound, I didn’t want to go through all that pain again… but I heard it, I heard the most beautiful sound of my entire life, those drums that go so fast, you can’t contain the happiness in your chest. “I would wait a lifetime to hold her in my arms” I had a very beautiful pregnancy, with lots of cravings, I ate all the time and slept with a jar of peanut butter next to me. My baby girl is 1 and a half months old, she is a very strong and beautiful girl, I would wait a lifetime to hold her in my arms. Her name is Barbara Rose, after my maternal grandmother. She passed away in 2017 and we were very close, my mommy, I’m sure put her hands on my belly and blessed it. I want to tell all women who are looking to have a baby not to give up, to do everything to achieve their dream, that everything is worth it.” Do you have ovarian cysts and want to have a baby? If you, like Jorley, live with ovarian cysts, don’t give up. There are many possibilities for you to fulfill your dream of becoming a mother through different assisted reproductive alternatives. Get in touch with Ingenes here! 

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5 de April, 2023 No Comments
Tasas de éxito Ingenes
Fertility

Success Rates: in Vitro Fertilization

What is in vitro fertilization and why choose Ingenes? Every couple starting an in vitro fertilization (IVF) treatment shares the same dream: to hold their baby. Choosing the right center can raise questions. Ingenes was the first in Mexico to publish its live birth rate online, surpassing the averages in Latin America and the United States so you can make a fully informed decision. What are Ingenes’ live birth rates per IVF cycle? These are our cumulative live birth rates: 1st cycle: up to 65% 2nd cycle: 75% 3rd cycle: up to 85% 4th cycle: 96% – the highest in Latin America We have 240% more treatments than the national average in Mexico (RedLara), positioning us as the leading center for high-complexity cases. Compare success rates in a natural cycle vs. an Ingenes cycle: Cumulative success rates per IVF cycle with Ingenes How are success rates measured and interpreted? Clinics use different metrics. These terms will help you understand them: Pregnancy rate: positive test after transfer. Implantation rate: gestational sacs by ultrasound ÷ embryos transferred. Clinical pregnancy rate: transfers showing a fetal heartbeat. Live birth rate: probability of achieving at least one baby per IVF cycle. Remember that every pregnancy carries a 15–20% risk of miscarriage. At Ingenes, we focus on live birth outcomes. Factors influencing IVF success Age: rates vary by life stage. Complete sample: we accept all patients without filtering. Each cycle counts as an independent attempt. Rates certified and notarized for your peace of mind. We handle all cases, including high-complexity ones. Discover the secret to a successful IVF and learn about embryo transfer in our detailed guide. Frequently Asked Questions 1. What affects my chances of success? Your age, ovarian reserve, sperm quality, and uterine health play key roles. Women under 35 tend to have higher live birth chances. Lifestyle factors like weight, smoking, and alcohol also matter. We customize your protocol with precise gonadotropin doses. At Ingenes, we measure your AMH levels and antral follicle count to tailor every step. Avoid self-medication: always consult a specialist. 2. How many IVF cycles will I need? Most conceive within the first two cycles, but some need three or four. By the fourth cycle, we reach a 96% cumulative rate. Each attempt adds to your overall probability. Talk to your doctor to align expectations. Your care is personalized: avoid comparing your process with general statistics. 3. Are there risks or side effects? Medications can cause ovarian hyperstimulation in rare cases. It’s normal to feel abdominal bloating, mild discomfort, and mood changes. We monitor you with ultrasounds and hCG and estradiol tests to minimize risks. Always follow your specialist’s dosing plan and report any serious symptoms immediately. 4. How soon can I resume my activities? After transfer, most people return to light routines within 24 hours. Avoid intense exercise and lifting over 5 kg for one week. Sexual activity can resume in a few days based on your doctor’s advice. Stress management is crucial: practice gentle yoga, meditation, or breathing techniques. Maintain a balanced diet and drink at least 2 L of water daily to support implantation. Sources American Society for Reproductive Medicine. (2022). Definitions of ART Terms. MedlinePlus. (2023). In vitro fertilization. Centers for Disease Control and Prevention. (2022). ART Success Rates. European Society of Human Reproduction and Embryology. (2021). Good Practice Guidelines for IVF. We’re with you every step of the way. If you have questions or need personalized guidance, consult a reproductive specialist: your dream of becoming a parent deserves the best support.

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3 de April, 2023 No Comments
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Testimonials

“I had my baby at 49 thanks to egg donation.”

Endometriosis affects 10% of women of reproductive age worldwide. In Mexico there are around 7 million women living with this condition. Claudia is one of them and shares how, despite everything, she managed to have her little Arleth. What is endometriosis and how does it impact fertility? Endometriosis occurs when tissue similar to the endometrium grows outside the uterus, on the ovaries, fallopian tubes, or peritoneum. That tissue responds to your hormones just like normal endometrium, but causes scarring, chronic pain, and can affect your ovulation or the quality of your eggs. When adhesions form, sometimes the tubes become blocked or the ovaries don’t function the same. Therefore, if you want to increase your chances of pregnancy, it’s best to consult a reproductive specialist before self-medicating or trying treatments on your own. What assisted reproduction treatments exist for endometriosis? For mild to moderate cases, intrauterine insemination combined with ovarian stimulation (for example, between 150 and 225 IU of FSH) is a low-complexity option. When endometriosis is moderate to severe, in vitro fertilization (IVF) usually offers better success rates. At Ingenes we design multicycle programs where we adjust doses, monitor ovarian response in mL, and evaluate embryo quality before transfer. With our Initial Program we create a personalized plan based on your medical history and previous studies. My experience after more than 10 years trying to conceive “I had been trying for over 12 years. I underwent endometrial resection, had an ovary removed, and had four unsuccessful inseminations. Each failed attempt hurt, but I never lost hope. My advice: don’t self-medicate, trust a team of experts, and follow a comprehensive protocol to save time and energy.” Why choose a reproductive biology specialist? A reproductive biology specialist not only performs the procedure, but also diagnoses and manages endometriosis throughout the process. This helps avoid unnecessary surgeries, optimize each cycle, and improve implantation rates. Testimonials like “After 10 years and with uterine fibroids, I had my baby” or “I became a mom despite having endometriosis” show that with the right support, the dream of becoming parents is possible. Sources consulted National Institute of Child Health and Human Development. (2021). Endometriosis. MedlinePlus. https://medlineplus.gov/endometriosis.html Giudice, L. C. (2010). Clinical practice. Endometriosis. The New England Journal of Medicine, 362(25), 2389–2398. Harada, T., & Iwabe, T. (2014). Pathophysiology and management of endometriosis-associated infertility. Journal of Obstetrics and Gynaecology Research, 40(10), 1957–1964. Practice Committee of the American Society for Reproductive Medicine. (2012). Endometriosis and infertility: a committee opinion. Fertility and Sterility, 98(3), 591–598. Frequently asked questions about endometriosis and pregnancy Does it always prevent fertility? Not all women with endometriosis experience infertility, but 30% to 50% do have difficulty conceiving. Early diagnosis and timely treatment greatly improve pregnancy chances. How long until IVF results are seen? An IVF cycle usually shows results with the pregnancy test 2–3 weeks after egg retrieval. The transfer is done 3–5 days after fertilization and confirmation with beta-hCG at 12–14 days. Is laparoscopy recommended? Diagnostic and therapeutic laparoscopy can remove implants and adhesions, improving pelvic pain and tubal function in mild to moderate cases. In advanced stages, it’s necessary to balance removal with preserving ovarian reserve. What care is needed before and after a cycle? Before: maintain a BMI between 18 and 25 kg/m², take folic acid (400 µg/day), and avoid tobacco and alcohol. During: strictly follow ovarian stimulation and hormonal tests. After: relative rest, progesterone support, and regular ultrasound monitoring. We know how challenging this journey can be. We accompany you with empathy and professionalism. It’s always best to see an assisted fertilization specialist to receive the plan most suited to your case. You are not alone; your dream of having a child can become reality!

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26 de March, 2023 No Comments
Fertility

Infertility: Mom and CEO at the same time

Claire Tomkins was working in the energy industry when she started an In Vitro Fertilization (IVF) treatment. After six failed IVF cycles, three miscarriages, and finally, three children, her professional life took a turn. What she went through to become a mom inspired her to found Future Family, a company dedicated to providing support to couples struggling with infertility. “My personal experience inspired me to leverage technology and solve women’s health problems,” Tomkins shared with Fortune magazine. I always knew I wanted to found a company, but I didn’t know it would be in the reproductive health sector.” Infertility drove Claire to fulfill her dream Despite the obstacles and challenges, Claire managed to fulfill her dreams. And now, through the company she founded, she seeks to help people who are on the same path. “My experience was isolated, lonely, and difficult to bear. So, while I was in my past job, where I was responsible for helping consumers finance solar energy for their homes, I thought a lot about how we could make access to fertility treatments much more affordable and accessible [too].” Claire shares Claire applied some of the same ideas she worked with in the solar industry to her company. Now her mission is to make access to fertility care easier. The startup founded by Claire is dedicated to demystifying the fertility journey. “We’re now at that moment where planning for your future family will become as common as planning to buy a house or your career,” Tomkins told Forbes magazine. Assisted Reproduction makes future planning possible Future Family is a platform that provides support in different aspects of infertility. For example, it provides financing for treatments for women and couples so they can choose affordable monthly payments instead of a large upfront cost. “I realized that women like me, who were focused on being executives in companies and starting their families after 30, would need much more support and services than the previous generation.” Claire affirms Late motherhood: A rising trend More and more women are waiting until their 30s to start having children. While this can have benefits, including the opportunity to focus on their careers and relationships, it also has a significant downside when it comes to fertility. “I’m encouraging all women to take advantage and start planning for their future, rather than waiting until it’s too late.” Claire says Claire’s story is an example of how you can be a mom despite the challenges. And that even with obstacles, you can use them to achieve more dreams. Yes, we can.

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25 de March, 2023 No Comments
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Assisted Reproduction

PICSI technique: what you need to know about it

Did you know that In Vitro Fertilization has some variations according to your diagnosis to increase your chances of success? These are: In this article, we will explain what you need to know about the PICSI technique to achieve your baby. PICSI: the most advanced technique in Assisted Reproduction treatments When cases arise in which IVF by Intracytoplasmic Sperm Injection (ICSI) does not produce the desired results, fertility specialists recommend In Vitro Fertilization by PICSI, designed primarily to improve the practice of ICSI. The PICSI technique is specifically recommended in complicated cases of male infertility, in which spermatozoa are very scarce or have motility or morphology problems. How is IVF by PICSI performed? The process begins by preparing a sterile culture plate with three hyaluronic acid hydrogel microdots (a substance that aids implantation) on the inside bottom.  This plate has three raised locator lines on the outside bottom to help the reproductive specialist find the microdots.  Once the sperm adheres to the hyaluronic acid, the one most suitable for fertilization is selected and injected directly into the egg. Subsequently, the usual procedure of transferring the resulting embryo to the uterus for development continues. Looking to have your baby through PICSI IVF? At Ingenes we have the necessary equipment and technology to perform ICSI and PICSI techniques in case they are required in In Vitro Fertilization treatments, which we have perfected to create the Multicycle Programs and increase the possibility of having a baby at home. Interested in finding out which treatment is right for you? Schedule an appointment with our fertility experts and they will indicate the best option for you.

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20 de December, 2022 No Comments
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