At Ingenes, we are excited to announce that we will host two scientists from Oregon Health & Science University (OHSU), world leaders in gene therapy and reproductive biotechnology.
Together, we will advance the IVF MORE® (Magnetic Ovulatory Restoration) technique, an innovative approach designed to improve your egg quality and increase your chances of success in assisted reproduction.
What is IVF MORE® and how does it help you?
IVF MORE® combines nuclear transfer and mitochondrial replacement so your eggs regain energy and quality. We use 2 mL of optimized cell solutions and 0.5 mL of enriched media to restore mitochondrial function in eggs with low reserve.
It is especially indicated if you have had unsuccessful IVF cycles or low oocyte quality. With IVF MORE® we increase the viable embryo rate and improve implantation.
OHSU – Ingenes collaboration
During the visit of Doctors Shoukhrat Mitalipov and Nuria Martí-Gutiérrez, we will hold a Scientific Exchange on IVF MORE®. We will share ovarian restoration and stem cell reprogramming protocols.
With this alliance, we reaffirm our leadership in Latin America in nuclear transfer and gene therapy for assisted reproduction. If you want to increase your pregnancy options, consult an Assisted Reproduction specialist first.
First Ovarian Restoration Session
In the initial session, we apply follicular biopsy and mitochondrial reconstitution to rejuvenate your eggs. We extract somatic cells to obtain healthy mitochondria and incorporate them into the eggs via microinjection under a stereoscopic microscope.
This exclusive protocol offers an alternative to egg donation. Each plan is personalized after detailed serum hormone (KG) and AMH diagnostics. Avoid self-medication: trust your specialist.
The key role of our laboratory
Our laboratory features controlled-atmosphere incubators, time-lapse systems for embryo monitoring, and state-of-the-art sequencers. This way, we optimize every phase of IVF.
Here we perform preimplantation genetic testing (PGT) to ensure you transfer only top-quality embryos. Learn more about the vital role of the laboratory in our IVF process.
20 years of fertility innovation
In 2025, we celebrate 20 years of transforming lives with a multidisciplinary team and cutting-edge technology. If you’re ready to take the next step toward parenthood, IVF MORE® could be the answer you’ve been looking for. Contact our specialists and discover your personalized path.
Frequently Asked Questions
- Who are the OHSU specialists and what do they bring?
- Doctors Mitalipov and Martí-Gutiérrez are leaders in nuclear transfer and mitochondrial replacement. They bring advanced protocols to restore ovarian function for those with poor egg quality.
- How does IVF MORE® differ from conventional IVF?
- IVF MORE® adds healthy mitochondria and cellular reprogramming to enhance oocyte viability. This translates into higher embryo cleavage rates and better implantation, especially after failed cycles.
- At what age is it recommended?
- It is especially recommended for women with low ovarian reserve or over 38 years old. Each case is evaluated with hormonal tests (FSH, AMH) and ultrasound, and the appropriate hormone dosage is designed.
- What precautions should I take?
- Do not self-medicate. Have a complete hormonal profile done and share your history with your specialist. Maintaining a balanced diet, moderate exercise, and stress management improves your ovarian response.
Sources Consulted
- National Library of Medicine (2022). Mitochondrial Replacement Therapy. https://medlineplus.gov/mitochondrialreplacementtherapy
- Harvard T.H. Chan School of Public Health (2021). Assisted Reproductive Technologies. https://doi.org/10.1002/9781119156805
- ESHRE (2020). Guidelines on IVF. https://www.eshre.eu/Guidelines-and-Legal/Guidelines/IVF
- ASRM (2019). Nuclear Transfer in Human Embryos. Fertility and Sterility, 112(6), 1009-1020. https://doi.org/10.1016/j.fertnstert.2019.08.015
We know this journey can be challenging. You’re not alone! Consult an in vitro fertilization specialist for personalized guidance and support.